Strengthen cough to reduce aspiration

Trial ID
NCT05700825
Official Title
Rehabilitation of Airway Protection in Parkinson's Disease: Comparing In-person and Telehealth Service Delivery Models
Goal
Strengthen cough to reduce aspiration
Phase
PHASE2
Status
RECRUITING
Sponsor
Teachers College, Columbia University
Study Type
INTERVENTIONAL
Enrollment
120 participants
Conditions
Parkinson Disease, Dysphagia
Interventions
Expiratory Muscle Strength Training + Cough Skill Training

Plain-Language Summary

The goal is to improve airway protection so people with Parkinson's swallow more safely and have fewer episodes of choking or food and liquids entering the lungs. The program uses expiratory muscle strength training to strengthen the muscles you use to breathe out so you can generate a stronger, more effective cough, plus cough skill training to teach timing and technique, and it is being tested both in person and via telehealth to see if remote delivery works as well. This is a behavioral exercise program, not a drug, so it does not interact with levodopa or other Parkinson's medications. They are enrolling people ages 50 to 90 with Parkinson's at Hoehn and Yahr stages II to IV who show airway protection problems on instrumental swallowing tests or a weak voluntary cough, are not currently doing exercise-based swallowing therapy, and who do not have other neurologic, serious respiratory, recent smoking, uncontrolled hypertension, or severe cognitive or psychiatric issues.

Locations

  • Purdue University, West Lafayette, Indiana, United States
  • Teachers College, Columbia University, New York, New York, United States

Frequently Asked Questions

What is this trial testing?
This trial is studying Expiratory Muscle Strength Training + Cough Skill Training. The goal is to improve airway protection so people with Parkinson's swallow more safely and have fewer episodes of choking or food and liquids entering the lungs. The program uses expiratory muscle strength training to strengthen the muscles you use to breathe out so you can generate a stronger, more effective cough, plus cough skill training to teach timing and technique, and it is being tested both in person and via telehealth to see if remote delivery works as well. This is a behavioral exercise program, not a drug, so it does not interact with levodopa or other Parkinson's medications. They are enrolling people ages 50 to 90 with Parkinson's at Hoehn and Yahr stages II to IV who show airway protection problems on instrumental swallowing tests or a weak voluntary cough, are not currently doing exercise-based swallowing therapy, and who do not have other neurologic, serious respiratory, recent smoking, uncontrolled hypertension, or severe cognitive or psychiatric issues.
Who can participate?
Participants must be between 50 Years and 90 Years.
Where is this trial located?
This trial is recruiting at 2 locations.
Does it cost anything to join?
No. There is no cost to participate. Study-related care and treatment are provided at no charge.
How long does the trial last?
This Phase 2 trial is estimated to last approximately 5 years and 1 month.

View on ClinicalTrials.gov