Improve cognition through supervised exercise
- Trial ID
- NCT05720468
- Official Title
- Exercise for Cognitive Excellence in Parkinson's Disease
- Goal
- Improve cognition through supervised exercise
- Phase
- NA
- Status
- RECRUITING
- Sponsor
- University of California, San Francisco
- Study Type
- INTERVENTIONAL
- Enrollment
- 32 participants
- Conditions
- Parkinson Disease
- Interventions
- Exercise, No Exercise
Plain-Language Summary
The goal is to find out whether a structured, virtually supervised exercise program can preserve or improve thinking and memory in people with Parkinson's. The approach uses regular moderate intensity workouts delivered online to raise heart rate, boost brain blood flow and neurotrophic support, and track changes in cerebrospinal fluid biomarkers via lumbar puncture, with results compared to a no-exercise group. Participants are asked to keep Parkinson's medications stable so the effects of exercise are tested on top of usual treatment. The trial is enrolling people age 40 to 80 with idiopathic Parkinson's and Hoehn and Yahr stage under 4 who can safely exercise and have MoCA scores of 23 or higher; people with uncontrolled medical problems, significant depression, high fall risk, heavy regular exercisers, or lack of access to the virtual program are excluded.
Locations
- University of California San Francisco, San Francisco, California, United States
Frequently Asked Questions
- What is this trial testing?
- This trial is studying Exercise. The goal is to find out whether a structured, virtually supervised exercise program can preserve or improve thinking and memory in people with Parkinson's. The approach uses regular moderate intensity workouts delivered online to raise heart rate, boost brain blood flow and neurotrophic support, and track changes in cerebrospinal fluid biomarkers via lumbar puncture, with results compared to a no-exercise group. Participants are asked to keep Parkinson's medications stable so the effects of exercise are tested on top of usual treatment. The trial is enrolling people age 40 to 80 with idiopathic Parkinson's and Hoehn and Yahr stage under 4 who can safely exercise and have MoCA scores of 23 or higher; people with uncontrolled medical problems, significant depression, high fall risk, heavy regular exercisers, or lack of access to the virtual program are excluded.
- Who can participate?
- Participants must be between 40 Years and 80 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- No. There is no cost to participate. Study-related care and treatment are provided at no charge.
- How long does the trial last?
- This trial is estimated to last approximately 3 years and 4 months.