Rehabilitation for Parkinson's (NCT05748028)
Reduce pain and autonomic symptoms
- Trial ID
- NCT05748028
- Official Title
- Pain and Autonomic Symptoms in Parkinson's Disease and Atypical Parkinsonisms: Identification of Predictive Patterns of Rehabilitation Outcome and Evaluation of the Impact on Quality of Life
- Goal
- Reduce pain and autonomic symptoms
- Status
- RECRUITING
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
- Study Type
- OBSERVATIONAL
- Enrollment
- 280 participants
- Conditions
- Parkinson Disease, Multiple System Atrophy
- Interventions
- Rehabilitation, Administration of Clinical scales
Summary For Families
The goal is to find which patterns of pain and autonomic symptoms, like dizziness when standing, constipation, urinary problems, or abnormal sweating, predict who will get the most benefit from rehabilitation and how those symptoms shape quality of life for people with Parkinson's disease or multiple system atrophy. Participants take part in rehabilitation focused on improving mobility, reducing pain, and managing autonomic problems, while researchers use validated clinical scales to measure pain, orthostatic blood pressure changes, bowel and bladder symptoms, mood, and quality of life, then link those measures to rehab outcomes. The study is looking for adults 18 and older with a clinical diagnosis of Parkinson's disease or MSA and a Mini-Mental State Examination score of at least 10, and it excludes people with vascular or drug-induced parkinsonism, diabetes, major liver or kidney disorders, thyroid disease, or use of potentially neurotoxic drugs.
Locations
- ICS Maugeri - IRCCS of Telese Terme, Telese Terme, Benevento, Italy
- ICS Maugeri - Lumezzane, Lumezzane, Brescia, Italy
- ICS Maugeri - Castelgoffredo, Castel Goffredo, Mantova, Italy
- ICS Maugeri - Mistretta, Mistretta, Messina, Italy
- ICS Maugeri - Veruno, Veruno, Novara, Italy
- ICS Maugeri - Montescano, Montescano, Pavia, Italy
- ICS Maugeri - Milano, Milan, Italy
- ICS Maugeri - Pavia Boezio, Pavia, Italy
- ICS Maugeri - Pavia, Pavia, Italy
Frequently Asked Questions
- What is this trial testing?
- This trial is studying Rehabilitation. The goal is to find which patterns of pain and autonomic symptoms, like dizziness when standing, constipation, urinary problems, or abnormal sweating, predict who will get the most benefit from rehabilitation and how those symptoms shape quality of life for people with Parkinson's disease or multiple system atrophy. Participants take part in rehabilitation focused on improving mobility, reducing pain, and managing autonomic problems, while researchers use validated clinical scales to measure pain, orthostatic blood pressure changes, bowel and bladder symptoms, mood, and quality of life, then link those measures to rehab outcomes. The study is looking for adults 18 and older with a clinical diagnosis of Parkinson's disease or MSA and a Mini-Mental State Examination score of at least 10, and it excludes people with vascular or drug-induced parkinsonism, diabetes, major liver or kidney disorders, thyroid disease, or use of potentially neurotoxic drugs.
- Who can participate?
- Participants must be at least 18 Years.
- Where is this trial located?
- This trial is recruiting at 9 locations.
- Does it cost anything to join?
- You are never charged a fee to join a legitimate clinical trial, and the study treatment and study-specific tests are provided by the trial sponsor at no charge. In the US, routine care you would receive anyway can still be billed to you or your insurance; coverage rules differ by country, and trials in the UK and Canada usually run through public health systems. Travel, parking, and time are real costs, and some trials reimburse them while others do not. Before enrolling, ask the study coordinator to explain in writing what is and is not covered.
- How long does the trial last?
- This trial is estimated to last approximately 7 years and 4 months.
- Can I leave the trial if I change my mind?
- Yes. You can withdraw from any clinical trial at any time, for any reason, without affecting your standard medical care. Trials are voluntary by law. The team may ask if you are willing to do a brief exit visit so they can collect safety information, but you are not obligated.
- Can my spouse or care partner come with me to visits?
- In most cases yes, and it is often encouraged. Care partners can help with notes, questions, and getting home safely after a long visit. Some study assessments do need to happen one on one, but care partners are usually welcome for the rest of the appointment.
- Will I get a placebo in this trial?
- This is an observational study, so there is no placebo and no experimental treatment is assigned. Researchers observe and collect information while you continue your usual care.