Neuropsychological assessment for Parkinson's (NCT05808504)
Improve thinking with scalp stimulation
- Trial ID
- NCT05808504
- Official Title
- Investigation of the Benefits of Electrical Non-invasive Stimulation on Cognitive Symptoms in Parkinson's Disease
- Goal
- Improve thinking with scalp stimulation
- Phase
- NA
- Status
- ACTIVE_NOT_RECRUITING
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
- Study Type
- INTERVENTIONAL
- Enrollment
- 90 participants
- Conditions
- Parkinson Disease
- Interventions
- Neuropsychological assessment, Neurological assessment, Cognitive task, EEG, tACS (real or sham)
Summary For Families
The trial is testing whether non-invasive alternating electrical stimulation can improve cognitive symptoms in Parkinson's, by targeting the brain rhythms that support attention and memory. Participants receive transcranial alternating current stimulation, either real or sham, while researchers record EEG and run cognitive tasks, the weak scalp currents aim to nudge or re-synchronize neural oscillations and are used as an add-on rather than replacing levodopa or other meds. They are recruiting adults 18 to 75 with idiopathic Parkinson's and reasonably preserved cognition (MoCA 22 or higher), no deep brain stimulation, and no major other neurological or psychiatric disorders, with healthy adults included as controls.
Locations
- CHU de Rennes, Rennes, France
Frequently Asked Questions
- What is this trial testing?
- This trial is studying Neuropsychological assessment. The trial is testing whether non-invasive alternating electrical stimulation can improve cognitive symptoms in Parkinson's, by targeting the brain rhythms that support attention and memory. Participants receive transcranial alternating current stimulation, either real or sham, while researchers record EEG and run cognitive tasks, the weak scalp currents aim to nudge or re-synchronize neural oscillations and are used as an add-on rather than replacing levodopa or other meds. They are recruiting adults 18 to 75 with idiopathic Parkinson's and reasonably preserved cognition (MoCA 22 or higher), no deep brain stimulation, and no major other neurological or psychiatric disorders, with healthy adults included as controls.
- Who can participate?
- Participants must be between 18 Years and 75 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- You are never charged a fee to join a legitimate clinical trial, and the study treatment and study-specific tests are provided by the trial sponsor at no charge. In the US, routine care you would receive anyway can still be billed to you or your insurance; coverage rules differ by country, and trials in the UK and Canada usually run through public health systems. Travel, parking, and time are real costs, and some trials reimburse them while others do not. Before enrolling, ask the study coordinator to explain in writing what is and is not covered.
- How long does the trial last?
- This trial is estimated to last approximately 2 years and 11 months.
- Can I leave the trial if I change my mind?
- Yes. You can withdraw from any clinical trial at any time, for any reason, without affecting your standard medical care. Trials are voluntary by law. The team may ask if you are willing to do a brief exit visit so they can collect safety information, but you are not obligated.
- Can my spouse or care partner come with me to visits?
- In most cases yes, and it is often encouraged. Care partners can help with notes, questions, and getting home safely after a long visit. Some study assessments do need to happen one on one, but care partners are usually welcome for the rest of the appointment.
- Will I get a placebo in this trial?
- This is a crossover trial: instead of staying in one group, you move through a sequence of assignments, so you receive the active treatment during at least one period of the study. It also includes a placebo or sham phase, so you would be on that during another period. Ask the coordinator for the exact sequence and how long each phase lasts.
- What procedures are involved in this trial?
- Based on the protocol, this trial involves: Thinking & memory tests (non-invasive); Brain wave recording (EEG) (non-invasive). Confirm the full schedule with the study coordinator.