Improve gait using Percept neurostimulation
- Trial ID
- NCT05820074
- Official Title
- Investigating Neural Biomarkers for Gait in Parkinson's Patients
- Goal
- Improve gait using Percept neurostimulation
- Status
- RECRUITING
- Sponsor
- Swiss Federal Institute of Technology
- Study Type
- OBSERVATIONAL
- Enrollment
- 60 participants
- Conditions
- Parkinson Disease, Gait Disorders, Neurologic
- Interventions
- Neural Activity Recording, Movement Parameter Recording, Neuromodulation
Plain-Language Summary
They're looking for specific brain signal patterns tied to walking and balance problems in Parkinson's, so future brain stimulation can be timed or targeted better to reduce freezing, falls, and shuffling. The team records brain rhythms from the implanted Percept PC neurostimulator while tracking movement during walking, comparing data with stimulation turned off to identify electrical signatures that could guide how deep brain stimulation is adjusted alongside medications like levodopa. Adults 18 and up with non-tremor dominant idiopathic PD who have postural instability and gait disturbance, who already have a Percept PC and can tolerate being off stimulation, plus healthy controls without neurological or sensory issues, are being enrolled; people with MoCA under 20 or other interfering conditions are excluded.
Locations
- Cereneo, Vitznau, Canton of Lucerne, Switzerland
Frequently Asked Questions
- What is this trial testing?
- This trial is studying Neural Activity Recording. They're looking for specific brain signal patterns tied to walking and balance problems in Parkinson's, so future brain stimulation can be timed or targeted better to reduce freezing, falls, and shuffling. The team records brain rhythms from the implanted Percept PC neurostimulator while tracking movement during walking, comparing data with stimulation turned off to identify electrical signatures that could guide how deep brain stimulation is adjusted alongside medications like levodopa. Adults 18 and up with non-tremor dominant idiopathic PD who have postural instability and gait disturbance, who already have a Percept PC and can tolerate being off stimulation, plus healthy controls without neurological or sensory issues, are being enrolled; people with MoCA under 20 or other interfering conditions are excluded.
- Who can participate?
- Participants must be at least 18 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- No. There is no cost to participate. Study-related care and treatment are provided at no charge.
- How long does the trial last?
- This trial is estimated to last approximately 1 year and 11 months.