Link brain activity to mood
- Trial ID
- NCT05820425
- Official Title
- Local Fields Potentials of the Subthalamic Nucleus in Patients With Parkinson's Disease and Neuropsychiatric Fluctuations
- Goal
- Link brain activity to mood
- Status
- RECRUITING
- Sponsor
- University Hospital, Grenoble
- Study Type
- OBSERVATIONAL
- Enrollment
- 12 participants
- Conditions
- Parkinson Disease
- Interventions
- LFP and EEG recording
Plain-Language Summary
The goal is to find electrical patterns in the subthalamic nucleus and on scalp EEG that line up with neuropsychiatric fluctuations like mood swings or cognitive shifts in people with Parkinson's. Investigators will use the Percept® DBS system to record local field potentials from the implanted STN electrode, along with EEG and symptom questionnaires, to match real brain activity to patients' reported ups and downs while people stay on their usual therapies. They are looking for people aged 30 to 75 with Parkinson's who have motor fluctuations or dyskinesias, had bilateral STN Percept implantation within the past 10 days, can complete an OFF-state questionnaire, have no dementia (MoCA > 24), and no active psychosis or pregnancy.
Locations
- CHU Grenoble Alpes, Grenoble, France
Frequently Asked Questions
- What is this trial testing?
- This trial is studying LFP and EEG recording. The goal is to find electrical patterns in the subthalamic nucleus and on scalp EEG that line up with neuropsychiatric fluctuations like mood swings or cognitive shifts in people with Parkinson's. Investigators will use the Percept® DBS system to record local field potentials from the implanted STN electrode, along with EEG and symptom questionnaires, to match real brain activity to patients' reported ups and downs while people stay on their usual therapies. They are looking for people aged 30 to 75 with Parkinson's who have motor fluctuations or dyskinesias, had bilateral STN Percept implantation within the past 10 days, can complete an OFF-state questionnaire, have no dementia (MoCA > 24), and no active psychosis or pregnancy.
- Who can participate?
- Participants must be between 30 Years and 75 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- No. There is no cost to participate. Study-related care and treatment are provided at no charge.
- How long does the trial last?
- This trial is estimated to last approximately 1 year and 10 months.