Assess experimental pain in Parkinsons
- Trial ID
- NCT05981261
- Official Title
- Comparing Pain Intensity and Discomfort in Patients With Parkinson´s Disease and Healthy Controls During Inducement of Mechanical, Thermal, and Chemical Experimental Pain
- Goal
- Assess experimental pain in Parkinsons
- Phase
- NA
- Status
- RECRUITING
- Sponsor
- University of Aarhus
- Study Type
- INTERVENTIONAL
- Enrollment
- 63 participants
- Conditions
- Pain, Parkinson Disease
- Interventions
- inducement of experimental pain
Plain-Language Summary
The team is trying to find out whether people with Parkinson's feel pain differently than healthy people, and whether common treatments like levodopa or deep brain stimulation change how intense or unpleasant triggered pain feels. To do that, they will apply short, controlled mechanical, heat, and chemical stimuli to provoke experimental pain and then measure pain intensity and discomfort, this is an observational comparison rather than a drug test. They are enrolling adults into three groups: healthy volunteers, people with Parkinson's on levodopa, and people with Parkinson's who have DBS. People with other neurological or medical conditions that affect pain, dementia (MoCA score under 24), untreated depression (BDI 15 or higher), inability to cooperate, or regular use of painkillers other than paracetamol (acetaminophen) or NSAIDs unless judged stable by a doctor are excluded.
Locations
- aarhus university Hospital, Aarhus, Denmark
Frequently Asked Questions
- What is this trial testing?
- This trial is studying inducement of experimental pain. The team is trying to find out whether people with Parkinson's feel pain differently than healthy people, and whether common treatments like levodopa or deep brain stimulation change how intense or unpleasant triggered pain feels. To do that, they will apply short, controlled mechanical, heat, and chemical stimuli to provoke experimental pain and then measure pain intensity and discomfort, this is an observational comparison rather than a drug test. They are enrolling adults into three groups: healthy volunteers, people with Parkinson's on levodopa, and people with Parkinson's who have DBS. People with other neurological or medical conditions that affect pain, dementia (MoCA score under 24), untreated depression (BDI 15 or higher), inability to cooperate, or regular use of painkillers other than paracetamol (acetaminophen) or NSAIDs unless judged stable by a doctor are excluded.
- Who can participate?
- Eligibility criteria vary. Check the full listing on ClinicalTrials.gov for detailed inclusion and exclusion criteria.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- No. There is no cost to participate. Study-related care and treatment are provided at no charge.
- How long does the trial last?
- This trial is estimated to last approximately 3 years and 7 months.