Increase walking endurance through exercise
- Trial ID
- NCT06088355
- Official Title
- Moderate Versus High Volume Light-Moderate Intensity Exercise for People With Moderate Parkinson's Disease
- Goal
- Increase walking endurance through exercise
- Phase
- NA
- Status
- RECRUITING
- Sponsor
- VA Office of Research and Development
- Study Type
- INTERVENTIONAL
- Enrollment
- 123 participants
- Conditions
- Parkinson Disease, Movement Disorders, Neurodegeneration
- Interventions
- HV-PDAE: High Volume Partnered Dance Aerobic Exercise, MV-PDAE: Moderate Volume Partnered Dance Aerobic Exercise, MV-WALK: Moderate Volume Walking
Plain-Language Summary
The goal is to see whether higher versus moderate amounts of light-to-moderate aerobic exercise can improve walking, balance, and overall motor symptoms in people with moderate Parkinson's. Participants are randomized to high-volume partnered dance aerobic exercise, moderate-volume partnered dance, or moderate-volume walking; these programs use rhythmic, repetitive movement to raise heart rate, boost cardiovascular fitness, improve gait and balance, and may promote neuroplasticity that helps motor control. Assessments are done while people are OFF their antiparkinsonian medications to avoid dyskinesia and medication-related fluctuations, so exercise effects are measured independently; exercise does not replace levodopa but could complement its benefits. The study seeks adults 40 and older with definite Parkinson's in Hoehn and Yahr stages 2 to 3, a MoCA score above 17, the ability to walk at least 10 feet, and clear benefit from PD meds, and it excludes those with serious heart disease, recent stroke or brain injury, untreated major psychiatric illness, heavy alcohol or antipsychotic use, or other conditions that make exercise unsafe.
Locations
- Atlanta VA Medical and Rehab Center, Decatur, GA, Decatur, Georgia, United States
Frequently Asked Questions
- What is this trial testing?
- This trial is studying HV-PDAE: High Volume Partnered Dance Aerobic Exercise. The goal is to see whether higher versus moderate amounts of light-to-moderate aerobic exercise can improve walking, balance, and overall motor symptoms in people with moderate Parkinson's. Participants are randomized to high-volume partnered dance aerobic exercise, moderate-volume partnered dance, or moderate-volume walking; these programs use rhythmic, repetitive movement to raise heart rate, boost cardiovascular fitness, improve gait and balance, and may promote neuroplasticity that helps motor control. Assessments are done while people are OFF their antiparkinsonian medications to avoid dyskinesia and medication-related fluctuations, so exercise effects are measured independently; exercise does not replace levodopa but could complement its benefits. The study seeks adults 40 and older with definite Parkinson's in Hoehn and Yahr stages 2 to 3, a MoCA score above 17, the ability to walk at least 10 feet, and clear benefit from PD meds, and it excludes those with serious heart disease, recent stroke or brain injury, untreated major psychiatric illness, heavy alcohol or antipsychotic use, or other conditions that make exercise unsafe.
- Who can participate?
- Participants must be at least 40 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- No. There is no cost to participate. Study-related care and treatment are provided at no charge.
- How long does the trial last?
- This trial is estimated to last approximately 3 years.