Cueing app for Parkinson's (NCT06142448)

Improve walking using auditory cueing

Trial ID
NCT06142448
Official Title
Unravelling the Neural Mechanisms Underlying Compensation Strategies for Gait Impairments in Parkinson's Disease: a Transnational, Multimodal Approach
Goal
Improve walking using auditory cueing
Phase
NA
Status
RECRUITING
Sponsor
Radboud University Medical Center
Study Type
INTERVENTIONAL
Enrollment
384 participants
Conditions
Parkinson Disease
Interventions
Cueing app

Summary For Families

Goal: Learn how the brain uses external compensation strategies to improve walking problems in Parkinson's, like slow steps, unstable rhythm, and freezing, so clinicians can target the right neural pathways. Approach: Participants use a cueing app that delivers timed external signals, usually rhythmic auditory beats, to guide step timing and spacing, engaging attention and alternative motor circuits to bypass impaired automatic gait control. Eligibility: Adults 18 and older with idiopathic Parkinson's who can walk at least three minutes unaided (a cane is allowed), who have not used daily compensation strategies in the past month, and who do not have deep brain stimulation, severe hearing loss, or significant cognitive impairment (MMSE <21).

Locations

  • Radboudumc, Nijmegen, Netherlands

Frequently Asked Questions

What is this trial testing?
This trial is studying Cueing app. Goal: Learn how the brain uses external compensation strategies to improve walking problems in Parkinson's, like slow steps, unstable rhythm, and freezing, so clinicians can target the right neural pathways. Approach: Participants use a cueing app that delivers timed external signals, usually rhythmic auditory beats, to guide step timing and spacing, engaging attention and alternative motor circuits to bypass impaired automatic gait control. Eligibility: Adults 18 and older with idiopathic Parkinson's who can walk at least three minutes unaided (a cane is allowed), who have not used daily compensation strategies in the past month, and who do not have deep brain stimulation, severe hearing loss, or significant cognitive impairment (MMSE <21).
Who can participate?
Participants must be at least 18 Years.
Where is this trial located?
This trial is recruiting at 1 location.
Does it cost anything to join?
You are never charged a fee to join a legitimate clinical trial, and the study treatment and study-specific tests are provided by the trial sponsor at no charge. In the US, routine care you would receive anyway can still be billed to you or your insurance; coverage rules differ by country, and trials in the UK and Canada usually run through public health systems. Travel, parking, and time are real costs, and some trials reimburse them while others do not. Before enrolling, ask the study coordinator to explain in writing what is and is not covered.
How long does the trial last?
This trial is estimated to last approximately 3 years.
Can I leave the trial if I change my mind?
Yes. You can withdraw from any clinical trial at any time, for any reason, without affecting your standard medical care. Trials are voluntary by law. The team may ask if you are willing to do a brief exit visit so they can collect safety information, but you are not obligated.
Can my spouse or care partner come with me to visits?
In most cases yes, and it is often encouraged. Care partners can help with notes, questions, and getting home safely after a long visit. Some study assessments do need to happen one on one, but care partners are usually welcome for the rest of the appointment.
Will I get a placebo in this trial?
This trial has a group that receives no study treatment (you would continue your usual care) alongside the treatment group. Because assignment is random, you have about a 1 in 2 chance (roughly 50%) of being in the no-treatment group, assuming the groups are filled equally. Ask the coordinator to confirm the exact assignment ratio.

Related Reading

View on ClinicalTrials.gov