Identify candidates for gene therapy
- Trial ID
- NCT06151002
- Official Title
- PD Frontline, Part of RAPSODI GD (Remote Assessment of Parkinsonism Supporting Ongoing Development of Interventions in Gaucher's Disease) to Build an Online Trial-ready Cohort of GBA Genotyped People With Parkinson's
- Goal
- Identify candidates for gene therapy
- Status
- RECRUITING
- Sponsor
- University College London Hospitals
- Study Type
- OBSERVATIONAL
- Enrollment
- 4800 participants
- Conditions
- Parkinson Disease
Plain-Language Summary
The team is building an online, trial-ready group of people with Parkinson's whose GBA gene status is known, so future treatments aimed at GBA-related Parkinson's can find the right participants faster. They enroll people with a formal Parkinson's diagnosis and use remote assessments plus genetic testing to determine GBA variants, keeping participants in a registry for quick referral to GBA-focused studies; this is observational, not a treatment. Adults aged 18 to 90 with Parkinson's can join, but anyone already confirmed GBA-positive will be referred to the sister RAPSODI study instead. The study excludes other types of parkinsonism, other neurological disorders, and people taking medications known to cause parkinsonism.
Locations
- University College London (UCL), London, United Kingdom
Frequently Asked Questions
- What is this trial testing?
- This trial is studying an experimental treatment. The team is building an online, trial-ready group of people with Parkinson's whose GBA gene status is known, so future treatments aimed at GBA-related Parkinson's can find the right participants faster. They enroll people with a formal Parkinson's diagnosis and use remote assessments plus genetic testing to determine GBA variants, keeping participants in a registry for quick referral to GBA-focused studies; this is observational, not a treatment. Adults aged 18 to 90 with Parkinson's can join, but anyone already confirmed GBA-positive will be referred to the sister RAPSODI study instead. The study excludes other types of parkinsonism, other neurological disorders, and people taking medications known to cause parkinsonism.
- Who can participate?
- Participants must be between 18 Years and 90 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- No. There is no cost to participate. Study-related care and treatment are provided at no charge.
- How long does the trial last?
- This trial is estimated to last approximately 5 years.