Use kinematics to diagnose Parkinson
- Trial ID
- NCT06161636
- Official Title
- Contribution of the Kinematic Theory in the Early Differential Diagnosis of the Parkinson's Disease
- Goal
- Use kinematics to diagnose Parkinson
- Status
- RECRUITING
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
- Study Type
- OBSERVATIONAL
- Enrollment
- 90 participants
- Conditions
- Parkinson Disease, Healthy, Parkinsonian Syndromes
Summary For Families
The team aims to find out whether detailed movement analysis based on kinematic theory can help tell early Parkinson's disease apart from other parkinsonian syndromes and from normal aging. They use noninvasive recordings of speech and motor movements and apply kinematic modeling to quantify timing and movement trajectories, looking for objective signatures of impaired motor control; some assessments may be done after about 12 hours off antiparkinsonian medication so the results reflect the unmedicated state. The trial is enrolling people aged 50 to 75 with parkinsonism or a related syndrome who have had motor symptoms for six years or less, plus healthy volunteers. People with major cognitive impairment, other neurological diseases, certain prior oromandibular or laryngeal procedures, uncorrected deafness, or any contraindication to pupil dilation are excluded.
Locations
- CHUM/Université de Montréal, Montreal, Quebec, Canada
Frequently Asked Questions
- What is this trial testing?
- This trial is studying an experimental treatment. The team aims to find out whether detailed movement analysis based on kinematic theory can help tell early Parkinson's disease apart from other parkinsonian syndromes and from normal aging. They use noninvasive recordings of speech and motor movements and apply kinematic modeling to quantify timing and movement trajectories, looking for objective signatures of impaired motor control; some assessments may be done after about 12 hours off antiparkinsonian medication so the results reflect the unmedicated state. The trial is enrolling people aged 50 to 75 with parkinsonism or a related syndrome who have had motor symptoms for six years or less, plus healthy volunteers. People with major cognitive impairment, other neurological diseases, certain prior oromandibular or laryngeal procedures, uncorrected deafness, or any contraindication to pupil dilation are excluded.
- Who can participate?
- Participants must be between 50 Years and 75 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- No. There is no cost to participate. Study-related care and treatment are provided at no charge.
- How long does the trial last?
- This trial is estimated to last approximately 8 years and 9 months.
- Will I get the real drug or a placebo?
- It depends on the trial design. Some Parkinson's trials are placebo controlled, meaning a portion of participants get an inactive comparison while others get the experimental treatment. Some use crossover designs so everyone eventually receives the active treatment at some point. Observational trials do not use a placebo at all because they are not testing a new treatment. The consent form for any specific trial spells out the design and your odds of being assigned to placebo before you enroll.
- How often will I need to visit the study site?
- Visit frequency varies by trial. Many Parkinson's studies require an in person visit every 4 to 12 weeks during the active treatment phase, with shorter or longer gaps depending on the design. The site coordinator can give you the full visit schedule before you sign anything, so you know what the time commitment looks like.
- Can I leave the trial if I change my mind?
- Yes. You can withdraw from any clinical trial at any time, for any reason, without affecting your standard medical care. Trials are voluntary by law. The team may ask if you are willing to do a brief exit visit so they can collect safety information, but you are not obligated.
- Will travel or parking be reimbursed?
- Many trials reimburse for parking, mileage, and sometimes lodging if the site is far from your home. Reimbursement policies vary by sponsor and site. When you contact the trial team, ask specifically what is covered and how reimbursement is processed.
- Can my spouse or care partner come with me to visits?
- In most cases yes, and it is often encouraged. Care partners can help with notes, questions, and getting home safely after a long visit. Some study assessments do need to happen one on one, but care partners are usually welcome for the rest of the appointment.