Use kinematics to diagnose Parkinson
- Trial ID
- NCT06161636
- Official Title
- Contribution of the Kinematic Theory in the Early Differential Diagnosis of the Parkinson's Disease
- Goal
- Use kinematics to diagnose Parkinson
- Status
- RECRUITING
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
- Study Type
- OBSERVATIONAL
- Enrollment
- 90 participants
- Conditions
- Parkinson Disease, Healthy, Parkinsonian Syndromes
Plain-Language Summary
The team aims to find out whether detailed movement analysis based on kinematic theory can help tell early Parkinson's disease apart from other parkinsonian syndromes and from normal aging. They use noninvasive recordings of speech and motor movements and apply kinematic modeling to quantify timing and movement trajectories, looking for objective signatures of impaired motor control; some assessments may be done after about 12 hours off antiparkinsonian medication so the results reflect the unmedicated state. The trial is enrolling people aged 50 to 75 with parkinsonism or a related syndrome who have had motor symptoms for six years or less, plus healthy volunteers. People with major cognitive impairment, other neurological diseases, certain prior oromandibular or laryngeal procedures, uncorrected deafness, or any contraindication to pupil dilation are excluded.
Locations
- CHUM/Université de Montréal, Montreal, Quebec, Canada
Frequently Asked Questions
- What is this trial testing?
- This trial is studying an experimental treatment. The team aims to find out whether detailed movement analysis based on kinematic theory can help tell early Parkinson's disease apart from other parkinsonian syndromes and from normal aging. They use noninvasive recordings of speech and motor movements and apply kinematic modeling to quantify timing and movement trajectories, looking for objective signatures of impaired motor control; some assessments may be done after about 12 hours off antiparkinsonian medication so the results reflect the unmedicated state. The trial is enrolling people aged 50 to 75 with parkinsonism or a related syndrome who have had motor symptoms for six years or less, plus healthy volunteers. People with major cognitive impairment, other neurological diseases, certain prior oromandibular or laryngeal procedures, uncorrected deafness, or any contraindication to pupil dilation are excluded.
- Who can participate?
- Participants must be between 50 Years and 75 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- No. There is no cost to participate. Study-related care and treatment are provided at no charge.
- How long does the trial last?
- This trial is estimated to last approximately 8 years and 9 months.