Reduce exertion with adaptive stimulation
- Trial ID
- NCT06296810
- Official Title
- Implementation of Adaptive DBS to Offset STN Dysregulation During Exercise and Reduce Exertion in Parkinson's Disease
- Goal
- Reduce exertion with adaptive stimulation
- Status
- RECRUITING
- Sponsor
- University of Colorado, Denver
- Study Type
- OBSERVATIONAL
- Enrollment
- 10 participants
- Conditions
- Parkinson Disease
- Interventions
- aDBS
Plain-Language Summary
The goal is to see if adaptive deep brain stimulation can prevent abnormal subthalamic nucleus activity during exercise, so people with Parkinson's feel less exertion and fatigue while moving. The approach uses your already‑implanted Medtronic Sensight leads and Percept IPG to sense STN signals and automatically adjust stimulation strength in real time, stabilizing motor signals during activity rather than relying on a fixed setting, and it is a device change that works alongside your current medications and DBS hardware. The study seeks 20 to 70 year olds who already have a Sensight implant with a Percept IPG, can complete the exercise testing, and can give informed consent, with about 10 people expected to enroll.
Locations
- University of Colorado, Aurora, Colorado, United States
Frequently Asked Questions
- What is this trial testing?
- This trial is studying aDBS. The goal is to see if adaptive deep brain stimulation can prevent abnormal subthalamic nucleus activity during exercise, so people with Parkinson's feel less exertion and fatigue while moving. The approach uses your already‑implanted Medtronic Sensight leads and Percept IPG to sense STN signals and automatically adjust stimulation strength in real time, stabilizing motor signals during activity rather than relying on a fixed setting, and it is a device change that works alongside your current medications and DBS hardware. The study seeks 20 to 70 year olds who already have a Sensight implant with a Percept IPG, can complete the exercise testing, and can give informed consent, with about 10 people expected to enroll.
- Who can participate?
- Participants must be between 20 Years and 70 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- No. There is no cost to participate. Study-related care and treatment are provided at no charge.
- How long does the trial last?
- This trial is estimated to last approximately 1 year and 3 months.