Brain stimulation effects on thinking
- Trial ID
- NCT06329726
- Official Title
- Long-Term Behavioral and Cognitive Outcomes of Deep Brain Stimulation in Patients With Parkinson's Disease
- Goal
- Brain stimulation effects on thinking
- Status
- RECRUITING
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
- Study Type
- OBSERVATIONAL
- Enrollment
- 52 participants
- Conditions
- Parkinson Disease
- Interventions
- Clinical examinations and clinical scales administration
Plain-Language Summary
The goal is to track long-term behavioral and cognitive effects after subthalamic nucleus deep brain stimulation, and to compare those outcomes with people managed on best medical therapy. Participants have regular clinical exams and rating scales; DBS works by sending continuous electrical pulses to the subthalamic nucleus to normalize abnormal brain-circuit activity that causes motor symptoms, often letting people reduce levodopa doses, though it can also change mood, impulse control, and some aspects of thinking. The study is enrolling adults 18 to 70 who are either candidates for STN DBS or are on best medical treatment, excluding anyone unable to complete the assessments.
Locations
- Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Lombardy, Italy
Frequently Asked Questions
- What is this trial testing?
- This trial is studying Clinical examinations and clinical scales administration. The goal is to track long-term behavioral and cognitive effects after subthalamic nucleus deep brain stimulation, and to compare those outcomes with people managed on best medical therapy. Participants have regular clinical exams and rating scales; DBS works by sending continuous electrical pulses to the subthalamic nucleus to normalize abnormal brain-circuit activity that causes motor symptoms, often letting people reduce levodopa doses, though it can also change mood, impulse control, and some aspects of thinking. The study is enrolling adults 18 to 70 who are either candidates for STN DBS or are on best medical treatment, excluding anyone unable to complete the assessments.
- Who can participate?
- Participants must be between 18 Years and 70 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- No. There is no cost to participate. Study-related care and treatment are provided at no charge.
- How long does the trial last?
- This trial is estimated to last approximately 10 years.