Clinical examinations and clinical… for Parkinson's (NCT06329739)
Determine if mutation affects thinking
- Trial ID
- NCT06329739
- Official Title
- Genetics in Parkinson's Disease: Behavioral and Cognitive Outcomes in Patients Undergoing Dopaminergic Treatment
- Goal
- Determine if mutation affects thinking
- Status
- RECRUITING
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
- Study Type
- OBSERVATIONAL
- Enrollment
- 68 participants
- Conditions
- Parkinson Disease
- Interventions
- Clinical examinations and clinical scales administration
Summary For Families
The study is looking at whether having a Parkinson's-related genetic mutation changes thinking, mood, or behavior in people who are taking levodopa or dopamine agonist medications. Participants do an initial visit and then yearly tests, questionnaires, and standard clinical scales for five years, and researchers will compare the results from people with mutations to those without. Adults 18 and older with Parkinson's who are on levodopa or dopamine agonists and who have had genetic testing can join if they can give consent; people who have had deep brain stimulation are not eligible.
Locations
- Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy
Frequently Asked Questions
- What is this trial testing?
- This trial is studying Clinical examinations and clinical scales administration. The study is looking at whether having a Parkinson's-related genetic mutation changes thinking, mood, or behavior in people who are taking levodopa or dopamine agonist medications. Participants do an initial visit and then yearly tests, questionnaires, and standard clinical scales for five years, and researchers will compare the results from people with mutations to those without. Adults 18 and older with Parkinson's who are on levodopa or dopamine agonists and who have had genetic testing can join if they can give consent; people who have had deep brain stimulation are not eligible.
- Who can participate?
- Participants must be at least 18 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- You are never charged a fee to join a legitimate clinical trial, and the study treatment and study-specific tests are provided by the trial sponsor at no charge. In the US, routine care you would receive anyway can still be billed to you or your insurance; coverage rules differ by country, and trials in the UK and Canada usually run through public health systems. Travel, parking, and time are real costs, and some trials reimburse them while others do not. Before enrolling, ask the study coordinator to explain in writing what is and is not covered.
- How long does the trial last?
- This trial is estimated to last approximately 10 years.
- Can I leave the trial if I change my mind?
- Yes. You can withdraw from any clinical trial at any time, for any reason, without affecting your standard medical care. Trials are voluntary by law. The team may ask if you are willing to do a brief exit visit so they can collect safety information, but you are not obligated.
- Can my spouse or care partner come with me to visits?
- In most cases yes, and it is often encouraged. Care partners can help with notes, questions, and getting home safely after a long visit. Some study assessments do need to happen one on one, but care partners are usually welcome for the rest of the appointment.
- Will I get a placebo in this trial?
- This is an observational study, so there is no placebo and no experimental treatment is assigned. Researchers observe and collect information while you continue your usual care.
- How many visits does this trial involve?
- There will be an initial assessment and annual follow-up assessments for 5 years.
- What procedures are involved in this trial?
- Based on the protocol, this trial involves: Questionnaires & surveys (non-invasive). Confirm the full schedule with the study coordinator.