Distinguish essential tremor from Parkinsons
- Trial ID
- NCT06378619
- Official Title
- Machine Learning Analysis Of The Tapping Test And The Archimedean Spiral For The Differential Diagnosis Of Essential Tremor And Parkinson's Disease.
- Goal
- Distinguish essential tremor from Parkinsons
- Status
- RECRUITING
- Sponsor
- Consorci Sanitari de l'Alt Penedès i Garraf
- Study Type
- OBSERVATIONAL
- Enrollment
- 110 participants
- Conditions
- Tremor, Essential Tremor, Parkinson Disease
- Interventions
- Tapping Test, Archimedes Spiral
Summary For Families
The goal is to help neurologists tell Parkinson's tremor from essential tremor more reliably using simple hand tests and computer analysis. People will do a finger tapping test and draw an Archimedean spiral while researchers measure speed, rhythm, tremor amplitude and tracing stability, then machine learning looks for patterns like slowed, irregular tapping with position-dependent tremor in Parkinson's versus the more regular kinetic tremor of essential tremor. The trial is enrolling people aged 45 to 79 who either have early-stage Parkinson's tremor with bradykinesia and Hoehn and Yahr stage 1 to 2, or have essential tremor diagnosed for at least 3 years with no bradykinesia. Individuals on antipsychotics, antidepressants, dopaminergic agonists or primidone, those with dyskinesias, severe tremor that prevents tracing, significant neuropathy, cognitive or affective problems, alcoholism, dystonia, prior stroke, or conflicting trial participation are excluded.
Locations
- Hospital Sant Camil-Consorci Sanitari Alt'Pènedes i Garraf, Barcelona, Catalonia, Spain
Frequently Asked Questions
- What is this trial testing?
- This trial is studying Tapping Test. The goal is to help neurologists tell Parkinson's tremor from essential tremor more reliably using simple hand tests and computer analysis. People will do a finger tapping test and draw an Archimedean spiral while researchers measure speed, rhythm, tremor amplitude and tracing stability, then machine learning looks for patterns like slowed, irregular tapping with position-dependent tremor in Parkinson's versus the more regular kinetic tremor of essential tremor. The trial is enrolling people aged 45 to 79 who either have early-stage Parkinson's tremor with bradykinesia and Hoehn and Yahr stage 1 to 2, or have essential tremor diagnosed for at least 3 years with no bradykinesia. Individuals on antipsychotics, antidepressants, dopaminergic agonists or primidone, those with dyskinesias, severe tremor that prevents tracing, significant neuropathy, cognitive or affective problems, alcoholism, dystonia, prior stroke, or conflicting trial participation are excluded.
- Who can participate?
- Participants must be between 45 Years and 79 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- No. There is no cost to participate. Study-related care and treatment are provided at no charge.
- How long does the trial last?
- This trial is estimated to last approximately 2 years.
- Will I get the real drug or a placebo?
- It depends on the trial design. Some Parkinson's trials are placebo controlled, meaning a portion of participants get an inactive comparison while others get the experimental treatment. Some use crossover designs so everyone eventually receives the active treatment at some point. Observational trials do not use a placebo at all because they are not testing a new treatment. The consent form for any specific trial spells out the design and your odds of being assigned to placebo before you enroll.
- How often will I need to visit the study site?
- Visit frequency varies by trial. Many Parkinson's studies require an in person visit every 4 to 12 weeks during the active treatment phase, with shorter or longer gaps depending on the design. The site coordinator can give you the full visit schedule before you sign anything, so you know what the time commitment looks like.
- Can I leave the trial if I change my mind?
- Yes. You can withdraw from any clinical trial at any time, for any reason, without affecting your standard medical care. Trials are voluntary by law. The team may ask if you are willing to do a brief exit visit so they can collect safety information, but you are not obligated.
- Will travel or parking be reimbursed?
- Many trials reimburse for parking, mileage, and sometimes lodging if the site is far from your home. Reimbursement policies vary by sponsor and site. When you contact the trial team, ask specifically what is covered and how reimbursement is processed.
- Can my spouse or care partner come with me to visits?
- In most cases yes, and it is often encouraged. Care partners can help with notes, questions, and getting home safely after a long visit. Some study assessments do need to happen one on one, but care partners are usually welcome for the rest of the appointment.