Reduce tremor and improve movement
- Trial ID
- NCT06400017
- Official Title
- Mechanism and Application of Deep Brain Stimulation in the Treatment of Parkinson's Disease
- Goal
- Reduce tremor and improve movement
- Phase
- NA
- Status
- RECRUITING
- Sponsor
- Beijing Tiantan Hospital
- Study Type
- INTERVENTIONAL
- Enrollment
- 60 participants
- Conditions
- Parkinson's Disease and Parkinsonism
- Interventions
- microelectrode stimulation of DBS
Plain-Language Summary
The trial aims to clarify how deep brain stimulation of the subthalamic nucleus controls Parkinson's motor symptoms and to evaluate the mechanism and application of an MRI-compatible dual-channel DBS system. It uses microelectrode-guided bilateral STN DBS with a 3.0T-compatible G106R/G106RS device, delivering continuous electrical pulses to rebalance abnormal motor circuits, which can reduce tremor, rigidity, and slowness and often lets people lower their levodopa dose. Participants should be adults 50 to 70 years old with typical Parkinson's for less than 20 years who plan bilateral STN DBS, have no major cognitive impairment (MMSE ≥24, MoCA ≥18), and have no medical or MRI contraindications to surgery.
Locations
- Beijing Tiantan Hospital, Beijing, Beijing Municipality, China
Frequently Asked Questions
- What is this trial testing?
- This trial is studying microelectrode stimulation of DBS. The trial aims to clarify how deep brain stimulation of the subthalamic nucleus controls Parkinson's motor symptoms and to evaluate the mechanism and application of an MRI-compatible dual-channel DBS system. It uses microelectrode-guided bilateral STN DBS with a 3.0T-compatible G106R/G106RS device, delivering continuous electrical pulses to rebalance abnormal motor circuits, which can reduce tremor, rigidity, and slowness and often lets people lower their levodopa dose. Participants should be adults 50 to 70 years old with typical Parkinson's for less than 20 years who plan bilateral STN DBS, have no major cognitive impairment (MMSE ≥24, MoCA ≥18), and have no medical or MRI contraindications to surgery.
- Who can participate?
- Participants must be between 50 Years and 70 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- No. There is no cost to participate. Study-related care and treatment are provided at no charge.
- How long does the trial last?
- This trial is estimated to last approximately 1 year and 6 months.