exposure to pesticides for Parkinson's (NCT06420310)
Link pesticides to early Parkinson
- Trial ID
- NCT06420310
- Official Title
- Prevalence of Preclinical and Prodromal Parkinson´s Disease in Subjects Exposed to Pesticides
- Goal
- Link pesticides to early Parkinson
- Status
- RECRUITING
- Sponsor
- Hospital Universitario de Burgos
- Study Type
- OBSERVATIONAL
- Enrollment
- 260 participants
- Conditions
- Pesticide-Induced Parkinsonism
- Interventions
- exposure to pesticides
Summary For Families
Researchers want to know whether pesticide exposure raises the chance of developing Parkinson's by looking for early or hidden signs of the disease. They will compare 130 people who work with pesticides to 130 who do not, using questionnaires and urine tests to measure exposure, and they will look for early signs and biological markers while adjusting for age, gender, and other health factors. The project is based on the idea that pesticides might change how some genes work and damage the parts of cells that make energy, which could start the nerve changes linked to Parkinson's. The study is enrolling men and women aged 45 to 55, with cases made up of farmers exposed to pesticides and controls with no work exposure; participants must give consent and cannot have other significant neurological conditions.
Locations
- Hospital Universitario de Burgos, Burgos, Spain
Frequently Asked Questions
- What is this trial testing?
- This trial is studying exposure to pesticides. Researchers want to know whether pesticide exposure raises the chance of developing Parkinson's by looking for early or hidden signs of the disease. They will compare 130 people who work with pesticides to 130 who do not, using questionnaires and urine tests to measure exposure, and they will look for early signs and biological markers while adjusting for age, gender, and other health factors. The project is based on the idea that pesticides might change how some genes work and damage the parts of cells that make energy, which could start the nerve changes linked to Parkinson's. The study is enrolling men and women aged 45 to 55, with cases made up of farmers exposed to pesticides and controls with no work exposure; participants must give consent and cannot have other significant neurological conditions.
- Who can participate?
- Participants must be between 45 Years and 55 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- You are never charged a fee to join a legitimate clinical trial, and the study treatment and study-specific tests are provided by the trial sponsor at no charge. In the US, routine care you would receive anyway can still be billed to you or your insurance; coverage rules differ by country, and trials in the UK and Canada usually run through public health systems. Travel, parking, and time are real costs, and some trials reimburse them while others do not. Before enrolling, ask the study coordinator to explain in writing what is and is not covered.
- How long does the trial last?
- This trial is estimated to last approximately 4 years and 6 months.
- Can I leave the trial if I change my mind?
- Yes. You can withdraw from any clinical trial at any time, for any reason, without affecting your standard medical care. Trials are voluntary by law. The team may ask if you are willing to do a brief exit visit so they can collect safety information, but you are not obligated.
- Can my spouse or care partner come with me to visits?
- In most cases yes, and it is often encouraged. Care partners can help with notes, questions, and getting home safely after a long visit. Some study assessments do need to happen one on one, but care partners are usually welcome for the rest of the appointment.
- Will I get a placebo in this trial?
- This is an observational study, so there is no placebo and no experimental treatment is assigned. Researchers observe and collect information while you continue your usual care.
- What procedures are involved in this trial?
- Based on the protocol, this trial involves: Questionnaires & surveys (non-invasive). Confirm the full schedule with the study coordinator.