Assess taste function in Parkinsons
- Trial ID
- NCT06439355
- Official Title
- Single-center Study of Gustation in Idiopathic Parkinson's Disease and Lewy Body Disease Using Gustatory Evoked Potential Analysis
- Goal
- Assess taste function in Parkinsons
- Phase
- NA
- Status
- RECRUITING
- Sponsor
- Centre Hospitalier Universitaire Dijon
- Study Type
- INTERVENTIONAL
- Enrollment
- 66 participants
- Conditions
- Idiopathic Parkinson's Disease and Lewy Body Disease
- Interventions
- Fasting blood test, Subject interview, Motor assessment, Neurocognitive assessment, Nutritional assessment, Taste tests
Plain-Language Summary
The team is investigating how taste perception and the brain's electrical responses to taste are altered in people with idiopathic Parkinson's disease and Lewy body disease, to help explain common changes in appetite, weight and taste. Participants do taste tests while clinicians record gustatory evoked potentials, which are the electrical signals the nervous system makes in response to taste, plus fasting blood work and motor, cognitive and nutritional assessments to connect taste signal changes with disease features. Adults 18 and older can join, including people with diagnosed IPD or probable/possible LBD and healthy volunteers, and everyone must fast over 2 hours and have BMI under 30; excluded are folks with diabetes, pacemakers, heavy smoking (>4 cigarettes/day), pregnancy, very low cognitive scores (MMSE <15 or MoCA <10), or medications that affect taste. The single-center study in Dijon aims to enroll about 66 participants.
Locations
- Chu Dijon Bourgogne, Dijon, France
Frequently Asked Questions
- What is this trial testing?
- This trial is studying Fasting blood test. The team is investigating how taste perception and the brain's electrical responses to taste are altered in people with idiopathic Parkinson's disease and Lewy body disease, to help explain common changes in appetite, weight and taste. Participants do taste tests while clinicians record gustatory evoked potentials, which are the electrical signals the nervous system makes in response to taste, plus fasting blood work and motor, cognitive and nutritional assessments to connect taste signal changes with disease features. Adults 18 and older can join, including people with diagnosed IPD or probable/possible LBD and healthy volunteers, and everyone must fast over 2 hours and have BMI under 30; excluded are folks with diabetes, pacemakers, heavy smoking (>4 cigarettes/day), pregnancy, very low cognitive scores (MMSE <15 or MoCA <10), or medications that affect taste. The single-center study in Dijon aims to enroll about 66 participants.
- Who can participate?
- Participants must be at least 18 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- No. There is no cost to participate. Study-related care and treatment are provided at no charge.
- How long does the trial last?
- This trial is estimated to last approximately 1 year and 11 months.