Fasting blood test for Parkinson's (NCT06439355)
Assess taste function in Parkinsons
- Trial ID
- NCT06439355
- Official Title
- Single-center Study of Gustation in Idiopathic Parkinson's Disease and Lewy Body Disease Using Gustatory Evoked Potential Analysis
- Goal
- Assess taste function in Parkinsons
- Phase
- NA
- Status
- UNKNOWN
- Sponsor
- Centre Hospitalier Universitaire Dijon
- Study Type
- INTERVENTIONAL
- Enrollment
- 66 participants
- Conditions
- Idiopathic Parkinson's Disease and Lewy Body Disease
- Interventions
- Fasting blood test, Subject interview, Motor assessment, Neurocognitive assessment, Nutritional assessment, Taste tests
Summary For Families
The team is investigating how taste perception and the brain's electrical responses to taste are altered in people with idiopathic Parkinson's disease and Lewy body disease, to help explain common changes in appetite, weight and taste. Participants do taste tests while clinicians record gustatory evoked potentials, which are the electrical signals the nervous system makes in response to taste, plus fasting blood work and motor, cognitive and nutritional assessments to connect taste signal changes with disease features. Adults 18 and older can join, including people with diagnosed IPD or probable/possible LBD and healthy volunteers, and everyone must fast over 2 hours and have BMI under 30; excluded are folks with diabetes, pacemakers, heavy smoking (>4 cigarettes/day), pregnancy, very low cognitive scores (MMSE <15 or MoCA <10), or medications that affect taste. The single-center study in Dijon aims to enroll about 66 participants.
Locations
- Chu Dijon Bourgogne, Dijon, France
Frequently Asked Questions
- What is this trial testing?
- This trial is studying Fasting blood test. The team is investigating how taste perception and the brain's electrical responses to taste are altered in people with idiopathic Parkinson's disease and Lewy body disease, to help explain common changes in appetite, weight and taste. Participants do taste tests while clinicians record gustatory evoked potentials, which are the electrical signals the nervous system makes in response to taste, plus fasting blood work and motor, cognitive and nutritional assessments to connect taste signal changes with disease features. Adults 18 and older can join, including people with diagnosed IPD or probable/possible LBD and healthy volunteers, and everyone must fast over 2 hours and have BMI under 30; excluded are folks with diabetes, pacemakers, heavy smoking (>4 cigarettes/day), pregnancy, very low cognitive scores (MMSE <15 or MoCA <10), or medications that affect taste. The single-center study in Dijon aims to enroll about 66 participants.
- Who can participate?
- Participants must be at least 18 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- You are never charged a fee to join a legitimate clinical trial, and the study treatment and study-specific tests are provided by the trial sponsor at no charge. In the US, routine care you would receive anyway can still be billed to you or your insurance; coverage rules differ by country, and trials in the UK and Canada usually run through public health systems. Travel, parking, and time are real costs, and some trials reimburse them while others do not. Before enrolling, ask the study coordinator to explain in writing what is and is not covered.
- How long does the trial last?
- This trial is estimated to last approximately 1 year and 11 months.
- Can I leave the trial if I change my mind?
- Yes. You can withdraw from any clinical trial at any time, for any reason, without affecting your standard medical care. Trials are voluntary by law. The team may ask if you are willing to do a brief exit visit so they can collect safety information, but you are not obligated.
- Can my spouse or care partner come with me to visits?
- In most cases yes, and it is often encouraged. Care partners can help with notes, questions, and getting home safely after a long visit. Some study assessments do need to happen one on one, but care partners are usually welcome for the rest of the appointment.
- Will I get a placebo in this trial?
- There is no placebo group. Everyone receives an active treatment; the study compares one treatment against another.
- What procedures are involved in this trial?
- Based on the protocol, this trial involves: Blood draw (minimally invasive); Walking & movement tests (non-invasive). Confirm the full schedule with the study coordinator.