Detect Parkinson using breath microbiome
- Trial ID
- NCT06453226
- Official Title
- PArkinson's Non-Invasive Volatile ORganic Compound Analysis and Microbiome Assessment (PANORAMA) Study
- Goal
- Detect Parkinson using breath microbiome
- Status
- RECRUITING
- Sponsor
- Imperial College London
- Study Type
- OBSERVATIONAL
- Enrollment
- 120 participants
- Conditions
- Parkinson Disease
Plain-Language Summary
PANORAMA aims to find noninvasive signals in breath and stool that could help detect or track Parkinson's by spotting volatile organic compounds and gut microbiome patterns linked to the disease. The approach is to collect breath samples to measure volatile organic compounds, which are metabolic byproducts from the body and microbes that can change with illness, and stool samples for microbiome sequencing to see how bacterial communities differ in Parkinson's; no drugs or treatments are given. The study is enrolling adults 18 to 90, both people with confirmed or suspected Parkinson's who are having neurological assessment and healthy volunteers including partners or carers, and participants must be off antibiotics or probiotics for at least four weeks, have no diagnosed dysbiotic conditions, and be able to consent.
Locations
- Charing Cross Hospital, Imperial College London, London, United Kingdom
Frequently Asked Questions
- What is this trial testing?
- This trial is studying an experimental treatment. PANORAMA aims to find noninvasive signals in breath and stool that could help detect or track Parkinson's by spotting volatile organic compounds and gut microbiome patterns linked to the disease. The approach is to collect breath samples to measure volatile organic compounds, which are metabolic byproducts from the body and microbes that can change with illness, and stool samples for microbiome sequencing to see how bacterial communities differ in Parkinson's; no drugs or treatments are given. The study is enrolling adults 18 to 90, both people with confirmed or suspected Parkinson's who are having neurological assessment and healthy volunteers including partners or carers, and participants must be off antibiotics or probiotics for at least four weeks, have no diagnosed dysbiotic conditions, and be able to consent.
- Who can participate?
- Participants must be between 18 Years and 90 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- No. There is no cost to participate. Study-related care and treatment are provided at no charge.
- How long does the trial last?
- This trial is estimated to last approximately 1 year and 5 months.