Parkinson's Trial NCT06501469
Distinguish Parkinson from similar conditions
- Trial ID
- NCT06501469
- Official Title
- Prospective, Observational Study to Identify Biomarkers in Parkinsonian Syndromes
- Goal
- Distinguish Parkinson from similar conditions
- Status
- ACTIVE_NOT_RECRUITING
- Sponsor
- Non-profit organization for scientific research in Parkinson's disease and related disorders
- Study Type
- OBSERVATIONAL
- Enrollment
- 200 participants
- Conditions
- Parkinson Disease, Progressive Supranuclear Palsy, Multiple System Atrophy, Atypical Parkinsonism, Parkinsonism
Summary For Families
The goal is to identify biological markers that can tell Parkinson's disease apart from related parkinsonian syndromes and track disease progression, so diagnosis and future treatments can be improved. The team will observe participants over time and collect clinical data, imaging, blood or CSF samples, and digital/monitoring data to find molecules or patterns linked to specific diagnoses and symptoms, no experimental drug is given, and current treatments like levodopa are recorded to see how biomarkers relate to medication response. People who can give written consent are eligible, including those with parkinsonism of any duration and healthy controls; excluded are drug- or metabolic-induced parkinsonism, structural brain lesions that explain symptoms, other serious illnesses with life expectancy under five years, or active participation in other interventional trials.
Locations
- HYGEIA Hospital, Parkinson's disease and Movement Disorders Department, Athens, Greece
Frequently Asked Questions
- What is this trial testing?
- This trial is studying an experimental treatment. The goal is to identify biological markers that can tell Parkinson's disease apart from related parkinsonian syndromes and track disease progression, so diagnosis and future treatments can be improved. The team will observe participants over time and collect clinical data, imaging, blood or CSF samples, and digital/monitoring data to find molecules or patterns linked to specific diagnoses and symptoms, no experimental drug is given, and current treatments like levodopa are recorded to see how biomarkers relate to medication response. People who can give written consent are eligible, including those with parkinsonism of any duration and healthy controls; excluded are drug- or metabolic-induced parkinsonism, structural brain lesions that explain symptoms, other serious illnesses with life expectancy under five years, or active participation in other interventional trials.
- Who can participate?
- Eligibility criteria vary. Check the full listing on ClinicalTrials.gov for detailed inclusion and exclusion criteria.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- You are never charged a fee to join a legitimate clinical trial, and the study treatment and study-specific tests are provided by the trial sponsor at no charge. In the US, routine care you would receive anyway can still be billed to you or your insurance; coverage rules differ by country, and trials in the UK and Canada usually run through public health systems. Travel, parking, and time are real costs, and some trials reimburse them while others do not. Before enrolling, ask the study coordinator to explain in writing what is and is not covered.
- How long does the trial last?
- This trial is estimated to last approximately 9 years and 2 months.
- Can I leave the trial if I change my mind?
- Yes. You can withdraw from any clinical trial at any time, for any reason, without affecting your standard medical care. Trials are voluntary by law. The team may ask if you are willing to do a brief exit visit so they can collect safety information, but you are not obligated.
- Can my spouse or care partner come with me to visits?
- In most cases yes, and it is often encouraged. Care partners can help with notes, questions, and getting home safely after a long visit. Some study assessments do need to happen one on one, but care partners are usually welcome for the rest of the appointment.
- Will I get a placebo in this trial?
- This is an observational study, so there is no placebo and no experimental treatment is assigned. Researchers observe and collect information while you continue your usual care.
- How many visits does this trial involve?
- You will be followed up for at least 5 years.