EVS and EEG for Parkinson's (NCT06506058)
Reduce freezing episodes while walking
- Trial ID
- NCT06506058
- Official Title
- Vestibular and Cortical Contributions to Transitions in Freezing of Gait in Parkinson's Disease
- Goal
- Reduce freezing episodes while walking
- Phase
- NA
- Status
- RECRUITING
- Sponsor
- University of Minnesota
- Study Type
- INTERVENTIONAL
- Enrollment
- 75 participants
- Conditions
- Parkinson Disease
- Interventions
- EVS and EEG
Summary For Families
Aiming to understand why people with Parkinson's suddenly freeze while walking, the team is studying how vestibular signals and brain activity drive those transitions. They use small, noninvasive electrical vestibular stimulation applied by electrodes near the ears to gently perturb balance signals that influence gait, while scalp EEG records the timing and patterns of cortical activity to see what precedes or follows freezing; this is a probe, not a drug, so it does not interact with levodopa. The study is recruiting people with Parkinson's age 40 to 80, with and without freezing, plus healthy age-matched controls (40 to 80) and younger controls (21 to 44), all able to walk 50 meters unaided, and excludes people with pacemakers or implanted brain devices, vestibular or visual disorders, seizures or recent head injury, and pregnancy.
Locations
- University of Minnesota, Movement Disorders Lab, Minneapolis, Minnesota, United States
Frequently Asked Questions
- What is this trial testing?
- This trial is studying EVS and EEG. Aiming to understand why people with Parkinson's suddenly freeze while walking, the team is studying how vestibular signals and brain activity drive those transitions. They use small, noninvasive electrical vestibular stimulation applied by electrodes near the ears to gently perturb balance signals that influence gait, while scalp EEG records the timing and patterns of cortical activity to see what precedes or follows freezing; this is a probe, not a drug, so it does not interact with levodopa. The study is recruiting people with Parkinson's age 40 to 80, with and without freezing, plus healthy age-matched controls (40 to 80) and younger controls (21 to 44), all able to walk 50 meters unaided, and excludes people with pacemakers or implanted brain devices, vestibular or visual disorders, seizures or recent head injury, and pregnancy.
- Who can participate?
- Participants must be between 21 Years and 80 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- You are never charged a fee to join a legitimate clinical trial, and the study treatment and study-specific tests are provided by the trial sponsor at no charge. In the US, routine care you would receive anyway can still be billed to you or your insurance; coverage rules differ by country, and trials in the UK and Canada usually run through public health systems. Travel, parking, and time are real costs, and some trials reimburse them while others do not. Before enrolling, ask the study coordinator to explain in writing what is and is not covered.
- How long does the trial last?
- This trial is estimated to last approximately 3 years and 8 months.
- Can I leave the trial if I change my mind?
- Yes. You can withdraw from any clinical trial at any time, for any reason, without affecting your standard medical care. Trials are voluntary by law. The team may ask if you are willing to do a brief exit visit so they can collect safety information, but you are not obligated.
- Can my spouse or care partner come with me to visits?
- In most cases yes, and it is often encouraged. Care partners can help with notes, questions, and getting home safely after a long visit. Some study assessments do need to happen one on one, but care partners are usually welcome for the rest of the appointment.
- Will I get a placebo in this trial?
- There is no placebo group. Everyone receives an active treatment; the study compares one treatment against another.
- What procedures are involved in this trial?
- Based on the protocol, this trial involves: Brain surgery / implanted device (invasive); Brain wave recording (EEG) (non-invasive). Confirm the full schedule with the study coordinator.