Immediate treatment for Parkinson's (NCT06540989)
Improve speech clarity with feedback
- Trial ID
- NCT06540989
- Official Title
- Understand Me for Life: Using Noise-augmented Automatic Speech Recognition to Improve Intelligibility in Parkinson's Disease
- Goal
- Improve speech clarity with feedback
- Phase
- EARLY_PHASE1
- Status
- RECRUITING
- Sponsor
- Teachers College, Columbia University
- Study Type
- INTERVENTIONAL
- Enrollment
- 42 participants
- Conditions
- Parkinson Disease
- Interventions
- Immediate treatment, Deferred treatment
Summary For Families
Understand Me for Life aims to make everyday speech clearer for people with Parkinson's who have mild to moderate trouble being understood, so conversations feel less tiring and more effective. It uses an automatic speech recognition system trained with noise-augmented audio to objectively measure intelligibility and give real-time feedback, helping participants practice louder, clearer articulation and better pacing; some start the program right away and others start later so outcomes can be compared. The trial is looking for people 50 to 80 years old with Parkinson's at Hoehn and Yahr stages I to IV, stable antiparkinsonian meds, a Mini‑Mental State Exam score of 25 or higher, and mild to moderate dysarthria. People with atypical parkinsonism, deep brain stimulation, recent intensive voice therapy, or unrelated speech or voice disorders are not eligible.
Locations
- Teachers College, Columbia University, New York, New York, United States
Frequently Asked Questions
- What is this trial testing?
- This trial is studying Immediate treatment. Understand Me for Life aims to make everyday speech clearer for people with Parkinson's who have mild to moderate trouble being understood, so conversations feel less tiring and more effective. It uses an automatic speech recognition system trained with noise-augmented audio to objectively measure intelligibility and give real-time feedback, helping participants practice louder, clearer articulation and better pacing; some start the program right away and others start later so outcomes can be compared. The trial is looking for people 50 to 80 years old with Parkinson's at Hoehn and Yahr stages I to IV, stable antiparkinsonian meds, a Mini‑Mental State Exam score of 25 or higher, and mild to moderate dysarthria. People with atypical parkinsonism, deep brain stimulation, recent intensive voice therapy, or unrelated speech or voice disorders are not eligible.
- Who can participate?
- Participants must be between 50 Years and 80 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- You are never charged a fee to join a legitimate clinical trial, and the study treatment and study-specific tests are provided by the trial sponsor at no charge. In the US, routine care you would receive anyway can still be billed to you or your insurance; coverage rules differ by country, and trials in the UK and Canada usually run through public health systems. Travel, parking, and time are real costs, and some trials reimburse them while others do not. Before enrolling, ask the study coordinator to explain in writing what is and is not covered.
- How long does the trial last?
- This Phase 1 trial is estimated to last approximately 1 year and 5 months.
- Can I leave the trial if I change my mind?
- Yes. You can withdraw from any clinical trial at any time, for any reason, without affecting your standard medical care. Trials are voluntary by law. The team may ask if you are willing to do a brief exit visit so they can collect safety information, but you are not obligated.
- Can my spouse or care partner come with me to visits?
- In most cases yes, and it is often encouraged. Care partners can help with notes, questions, and getting home safely after a long visit. Some study assessments do need to happen one on one, but care partners are usually welcome for the rest of the appointment.
- Will I get a placebo in this trial?
- There is no placebo group. Everyone receives an active treatment; the study compares one treatment against another.
- How many visits does this trial involve?
- The study involves 5-7 assessment sessions (including a 6-month follow-up) and 16 treatment sessions, and participants are expected to be involved for 7-8 months.
- What procedures are involved in this trial?
- Based on the protocol, this trial involves: Questionnaires & surveys (non-invasive). Confirm the full schedule with the study coordinator.