Reduce motor and nonmotor symptoms
- Trial ID
- NCT06548256
- Official Title
- The Clinical Application of Clostridium Butyricum Miyairisan for Motor and Non-motor Symptoms in Parkinson's Disease
- Goal
- Reduce motor and nonmotor symptoms
- Phase
- NA
- Status
- RECRUITING
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
- Study Type
- INTERVENTIONAL
- Enrollment
- 400 participants
- Conditions
- Clostridium Butyricum Miyairi, Parkinson Disease
- Interventions
- Miyarisan-BM (Clostridium Butyricum Miyairi)
Plain-Language Summary
The trial is testing whether the probiotic Clostridium butyricum Miyairisan can help improve motor and non-motor Parkinson's symptoms, especially gut-related problems that can worsen medication response. Miyarisan-BM is a live probiotic that produces butyrate and helps rebalance the gut microbiome, which may reduce intestinal inflammation, ease constipation, strengthen the gut barrier, and indirectly affect how levodopa is absorbed and how well motor symptoms are controlled. People aged 20 to 90 with Parkinson's disease can join, but those with Parkinson's disease dementia or lactose intolerance are excluded.
Locations
- Kaohsiung Medical Univeristy Hospital, Kaohsiung City, Taiwan
Frequently Asked Questions
- What is this trial testing?
- This trial is studying Miyarisan-BM (Clostridium Butyricum Miyairi). The trial is testing whether the probiotic Clostridium butyricum Miyairisan can help improve motor and non-motor Parkinson's symptoms, especially gut-related problems that can worsen medication response. Miyarisan-BM is a live probiotic that produces butyrate and helps rebalance the gut microbiome, which may reduce intestinal inflammation, ease constipation, strengthen the gut barrier, and indirectly affect how levodopa is absorbed and how well motor symptoms are controlled. People aged 20 to 90 with Parkinson's disease can join, but those with Parkinson's disease dementia or lactose intolerance are excluded.
- Who can participate?
- Participants must be between 20 Years and 90 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- No. There is no cost to participate. Study-related care and treatment are provided at no charge.
- How long does the trial last?
- This trial is estimated to last approximately 3 years and 2 months.