Enhance Parkinsons cognition via exercise
- Trial ID
- NCT06580977
- Official Title
- Exploring the Effects of Exercise on Memory and Cognition in Parkinson´s Disease
- Goal
- Enhance Parkinsons cognition via exercise
- Phase
- NA
- Status
- RECRUITING
- Sponsor
- Heidelberg University
- Study Type
- INTERVENTIONAL
- Enrollment
- 60 participants
- Conditions
- Parkinson Disease
- Interventions
- cardiovascular training, stretching
Plain-Language Summary
They want to know whether regular aerobic cardiovascular exercise can improve memory and other thinking skills that often decline in Parkinson's. Participants will do a supervised aerobic training program or a stretching program as a low-intensity comparison; the aerobic work raises heart rate to increase blood flow and oxygen delivery and to stimulate brain-supporting factors like BDNF that help learning and memory. Exercise does not directly change how levodopa works, so it is meant to complement existing medications rather than replace them. Looking for people aged 50 to 80 with Parkinson's at Hoehn and Yahr stage 3 or lower who can stand and walk 10 meters, are naive to the memory tests, have only mild or no cognitive impairment (MoCA 21+), no deep brain stimulation, no major psychiatric or other conditions that would interfere, and who are not already doing high levels of cardiovascular exercise.
Locations
- Heidelberg University, Heidelberg, Baden-Wurttemberg, Germany
Frequently Asked Questions
- What is this trial testing?
- This trial is studying cardiovascular training. They want to know whether regular aerobic cardiovascular exercise can improve memory and other thinking skills that often decline in Parkinson's. Participants will do a supervised aerobic training program or a stretching program as a low-intensity comparison; the aerobic work raises heart rate to increase blood flow and oxygen delivery and to stimulate brain-supporting factors like BDNF that help learning and memory. Exercise does not directly change how levodopa works, so it is meant to complement existing medications rather than replace them. Looking for people aged 50 to 80 with Parkinson's at Hoehn and Yahr stage 3 or lower who can stand and walk 10 meters, are naive to the memory tests, have only mild or no cognitive impairment (MoCA 21+), no deep brain stimulation, no major psychiatric or other conditions that would interfere, and who are not already doing high levels of cardiovascular exercise.
- Who can participate?
- Participants must be between 50 Years and 80 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- No. There is no cost to participate. Study-related care and treatment are provided at no charge.
- How long does the trial last?
- This trial is estimated to last approximately 2 years and 9 months.