Reduce motor symptoms using neurofeedback
- Trial ID
- NCT06582355
- Official Title
- MOTOR-NF - a Randomized Controlled Trial of FMRI-based Neurofeedback for Motor Symptoms of Parkinson's Disease
- Goal
- Reduce motor symptoms using neurofeedback
- Phase
- NA
- Status
- RECRUITING
- Sponsor
- Maastricht University Medical Center
- Study Type
- INTERVENTIONAL
- Enrollment
- 60 participants
- Conditions
- Parkinson Disease
- Interventions
- Neurofeedback, Kinesthetic imagery
Plain-Language Summary
It aims to help people with Parkinson's improve motor symptoms like slowness and stiffness by training the brain's motor networks. Using real-time fMRI neurofeedback plus kinesthetic imagery, participants watch live feedback of activity in their motor cortex and use imagined, felt movements to learn to increase or normalize that activity, a noninvasive brain-training approach that can be used alongside usual medications such as levodopa. They are enrolling adults 18 and older with Parkinson's in Hoehn and Yahr stages 1 to 3 who can safely have an MRI, score at least 24 on the MoCA, and have no history of psychotic or bipolar disorders, recent illegal drug use, or MRI-incompatible implants. About 60 people will be enrolled at Maastricht University Medical Center.
Locations
- Uniklinik Köln, Cologne, Germany
- Maastricht University, Maastricht, Netherlands
Frequently Asked Questions
- What is this trial testing?
- This trial is studying Neurofeedback. It aims to help people with Parkinson's improve motor symptoms like slowness and stiffness by training the brain's motor networks. Using real-time fMRI neurofeedback plus kinesthetic imagery, participants watch live feedback of activity in their motor cortex and use imagined, felt movements to learn to increase or normalize that activity, a noninvasive brain-training approach that can be used alongside usual medications such as levodopa. They are enrolling adults 18 and older with Parkinson's in Hoehn and Yahr stages 1 to 3 who can safely have an MRI, score at least 24 on the MoCA, and have no history of psychotic or bipolar disorders, recent illegal drug use, or MRI-incompatible implants. About 60 people will be enrolled at Maastricht University Medical Center.
- Who can participate?
- Participants must be at least 18 Years.
- Where is this trial located?
- This trial is recruiting at 2 locations.
- Does it cost anything to join?
- No. There is no cost to participate. Study-related care and treatment are provided at no charge.
- How long does the trial last?
- This trial is estimated to last approximately 1 year and 5 months.