Improve walking through cognitive rehabilitation
- Trial ID
- NCT06588920
- Official Title
- Brain Activity, Cognitive Function, and Walking Ability in People With Parkinson's Disease
- Goal
- Improve walking through cognitive rehabilitation
- Status
- RECRUITING
- Sponsor
- National Yang Ming Chiao Tung University
- Study Type
- OBSERVATIONAL
- Enrollment
- 70 participants
- Conditions
- Healthy Older Adults, Parkinson Disease
- Interventions
- Cognitive function, gait, and electroencephalogram
Summary For Families
The goal is to map how brain electrical activity, thinking skills, and walking relate in people with Parkinson's compared with healthy older adults, to spot patterns that might explain mobility or thinking problems. The team will record EEG while you do walking and cognitive tests, plus measure gait, so they can link specific brain signals to changes in thinking or walking; it is observational, not a drug trial, and participants should be on stable dopaminergic medication so findings reflect the usual effect of levodopa or similar drugs. Looking for adults 40 to 80 with idiopathic Parkinson's who can walk 10 meters unaided, have an MMSE of 24 or higher, at least junior high education, and no prior brain surgery or other major neurological, musculoskeletal, or cardiopulmonary conditions.
Locations
- National Yang Ming Chiao Tung University, Taipei, Taiwan
- National Yang Ming Chiao Tung University, Taipei, Taiwan
Frequently Asked Questions
- What is this trial testing?
- This trial is studying Cognitive function, gait, and electroencephalogram. The goal is to map how brain electrical activity, thinking skills, and walking relate in people with Parkinson's compared with healthy older adults, to spot patterns that might explain mobility or thinking problems. The team will record EEG while you do walking and cognitive tests, plus measure gait, so they can link specific brain signals to changes in thinking or walking; it is observational, not a drug trial, and participants should be on stable dopaminergic medication so findings reflect the usual effect of levodopa or similar drugs. Looking for adults 40 to 80 with idiopathic Parkinson's who can walk 10 meters unaided, have an MMSE of 24 or higher, at least junior high education, and no prior brain surgery or other major neurological, musculoskeletal, or cardiopulmonary conditions.
- Who can participate?
- Participants must be between 40 Years and 80 Years.
- Where is this trial located?
- This trial is recruiting at 2 locations.
- Does it cost anything to join?
- No. There is no cost to participate. Study-related care and treatment are provided at no charge.
- How long does the trial last?
- This trial is estimated to last approximately 2 years and 11 months.
- Will I get the real drug or a placebo?
- It depends on the trial design. Some Parkinson's trials are placebo controlled, meaning a portion of participants get an inactive comparison while others get the experimental treatment. Some use crossover designs so everyone eventually receives the active treatment at some point. Observational trials do not use a placebo at all because they are not testing a new treatment. The consent form for any specific trial spells out the design and your odds of being assigned to placebo before you enroll.
- How often will I need to visit the study site?
- Visit frequency varies by trial. Many Parkinson's studies require an in person visit every 4 to 12 weeks during the active treatment phase, with shorter or longer gaps depending on the design. The site coordinator can give you the full visit schedule before you sign anything, so you know what the time commitment looks like.
- Can I leave the trial if I change my mind?
- Yes. You can withdraw from any clinical trial at any time, for any reason, without affecting your standard medical care. Trials are voluntary by law. The team may ask if you are willing to do a brief exit visit so they can collect safety information, but you are not obligated.
- Will travel or parking be reimbursed?
- Many trials reimburse for parking, mileage, and sometimes lodging if the site is far from your home. Reimbursement policies vary by sponsor and site. When you contact the trial team, ask specifically what is covered and how reimbursement is processed.
- Can my spouse or care partner come with me to visits?
- In most cases yes, and it is often encouraged. Care partners can help with notes, questions, and getting home safely after a long visit. Some study assessments do need to happen one on one, but care partners are usually welcome for the rest of the appointment.