Distinguish reflexive tightness from stiffness
- Trial ID
- NCT06596187
- Official Title
- Differential Assessment of Hypertonia Related to CNS Impairment
- Goal
- Distinguish reflexive tightness from stiffness
- Phase
- NA
- Status
- RECRUITING
- Sponsor
- Chang Gung University
- Study Type
- INTERVENTIONAL
- Enrollment
- 45 participants
- Conditions
- SCI - Spinal Cord Injury, PD - Parkinson's Disease
- Interventions
- Continuous passive motion device (CPM) of ankle - fast, Continuous passive motion device (CPM) of ankle - slow
Plain-Language Summary
The goal is to tell apart different kinds of increased muscle tone from central nervous system problems, comparing people with chronic spinal cord injury to those with Parkinson's disease so clinicians can better recognize reflexive spasticity versus Parkinsonian stiffness. The approach uses a continuous passive motion device to move the ankle at slow and fast speeds, watching how muscles and reflexes respond to passive stretch, so faster stretches will highlight velocity-dependent reflex spasticity while slower movement reveals more constant rigidity; this is a device-based assessment rather than a drug treatment. Adults 20 and older with a clinical diagnosis of Parkinson's disease or with chronic spinal cord injury longer than one year can join, but people with leg musculoskeletal injuries or osteoporosis are excluded, and the SCI group also excludes pacemakers, current antispastic or antidepressant use, venous thromboembolism, or impaired soleus H-reflex function.
Locations
- Chang Gung University, Taoyuan District, Taiwan
Frequently Asked Questions
- What is this trial testing?
- This trial is studying Continuous passive motion device (CPM) of ankle - fast. The goal is to tell apart different kinds of increased muscle tone from central nervous system problems, comparing people with chronic spinal cord injury to those with Parkinson's disease so clinicians can better recognize reflexive spasticity versus Parkinsonian stiffness. The approach uses a continuous passive motion device to move the ankle at slow and fast speeds, watching how muscles and reflexes respond to passive stretch, so faster stretches will highlight velocity-dependent reflex spasticity while slower movement reveals more constant rigidity; this is a device-based assessment rather than a drug treatment. Adults 20 and older with a clinical diagnosis of Parkinson's disease or with chronic spinal cord injury longer than one year can join, but people with leg musculoskeletal injuries or osteoporosis are excluded, and the SCI group also excludes pacemakers, current antispastic or antidepressant use, venous thromboembolism, or impaired soleus H-reflex function.
- Who can participate?
- Participants must be at least 20 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- No. There is no cost to participate. Study-related care and treatment are provided at no charge.
- How long does the trial last?
- This trial is estimated to last approximately 1 year and 10 months.