Detect freezing through oculomotor markers

Trial ID
NCT06663826
Official Title
Development of Digital Diagnostic Devices for Parkinson's Disease
Goal
Detect freezing through oculomotor markers
Status
RECRUITING
Sponsor
machineMD AG
Study Type
OBSERVATIONAL
Enrollment
100 participants
Conditions
Parkinson Disease
Interventions
oculomotor and pupillary function assessment

Plain-Language Summary

They want to see whether digital measurements of eye movements and pupil reactions can reveal brain changes linked to walking problems in Parkinson's, especially daily freezing or festination. The study uses oculomotor and pupillary assessments recorded by digital devices, potentially at home over WiFi, to capture objective markers of balance and gait while allowing regular Parkinson's medications but excluding drugs that blunt eye responses. Looking for people with Parkinson's or atypical parkinsonism who can report daily freezing or festination, have a refractive error between -6 and +4 diopters, can walk unsupported or with an aid for at least five minutes, and who do not have other neurological diseases, eye or skin issues that affect measurements, interfering medications, severe cognitive problems, or poor home WiFi.

Locations

  • University Hospital of Zurich, Zurich, Canton of Zurich, Switzerland

Frequently Asked Questions

What is this trial testing?
This trial is studying oculomotor and pupillary function assessment. They want to see whether digital measurements of eye movements and pupil reactions can reveal brain changes linked to walking problems in Parkinson's, especially daily freezing or festination. The study uses oculomotor and pupillary assessments recorded by digital devices, potentially at home over WiFi, to capture objective markers of balance and gait while allowing regular Parkinson's medications but excluding drugs that blunt eye responses. Looking for people with Parkinson's or atypical parkinsonism who can report daily freezing or festination, have a refractive error between -6 and +4 diopters, can walk unsupported or with an aid for at least five minutes, and who do not have other neurological diseases, eye or skin issues that affect measurements, interfering medications, severe cognitive problems, or poor home WiFi.
Who can participate?
Eligibility criteria vary. Check the full listing on ClinicalTrials.gov for detailed inclusion and exclusion criteria.
Where is this trial located?
This trial is recruiting at 1 location.
Does it cost anything to join?
No. There is no cost to participate. Study-related care and treatment are provided at no charge.
How long does the trial last?
This trial is estimated to last approximately 1 year and 9 months.

View on ClinicalTrials.gov