oculomotor and pupillary function… for Parkinson's (NCT06663826)
Detect freezing through oculomotor markers
- Trial ID
- NCT06663826
- Official Title
- Development of Digital Diagnostic Devices for Parkinson's Disease
- Goal
- Detect freezing through oculomotor markers
- Status
- RECRUITING
- Sponsor
- machineMD AG
- Study Type
- OBSERVATIONAL
- Enrollment
- 100 participants
- Conditions
- Parkinson Disease
- Interventions
- oculomotor and pupillary function assessment
Summary For Families
They want to see whether digital measurements of eye movements and pupil reactions can reveal brain changes linked to walking problems in Parkinson's, especially daily freezing or festination. The study uses oculomotor and pupillary assessments recorded by digital devices, potentially at home over WiFi, to capture objective markers of balance and gait while allowing regular Parkinson's medications but excluding drugs that blunt eye responses. Looking for people with Parkinson's or atypical parkinsonism who can report daily freezing or festination, have a refractive error between -6 and +4 diopters, can walk unsupported or with an aid for at least five minutes, and who do not have other neurological diseases, eye or skin issues that affect measurements, interfering medications, severe cognitive problems, or poor home WiFi.
Locations
- University Hospital of Zurich, Zurich, Canton of Zurich, Switzerland
Frequently Asked Questions
- What is this trial testing?
- This trial is studying oculomotor and pupillary function assessment. They want to see whether digital measurements of eye movements and pupil reactions can reveal brain changes linked to walking problems in Parkinson's, especially daily freezing or festination. The study uses oculomotor and pupillary assessments recorded by digital devices, potentially at home over WiFi, to capture objective markers of balance and gait while allowing regular Parkinson's medications but excluding drugs that blunt eye responses. Looking for people with Parkinson's or atypical parkinsonism who can report daily freezing or festination, have a refractive error between -6 and +4 diopters, can walk unsupported or with an aid for at least five minutes, and who do not have other neurological diseases, eye or skin issues that affect measurements, interfering medications, severe cognitive problems, or poor home WiFi.
- Who can participate?
- Eligibility criteria vary. Check the full listing on ClinicalTrials.gov for detailed inclusion and exclusion criteria.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- You are never charged a fee to join a legitimate clinical trial, and the study treatment and study-specific tests are provided by the trial sponsor at no charge. In the US, routine care you would receive anyway can still be billed to you or your insurance; coverage rules differ by country, and trials in the UK and Canada usually run through public health systems. Travel, parking, and time are real costs, and some trials reimburse them while others do not. Before enrolling, ask the study coordinator to explain in writing what is and is not covered.
- How long does the trial last?
- This trial is estimated to last approximately 1 year and 9 months.
- Can I leave the trial if I change my mind?
- Yes. You can withdraw from any clinical trial at any time, for any reason, without affecting your standard medical care. Trials are voluntary by law. The team may ask if you are willing to do a brief exit visit so they can collect safety information, but you are not obligated.
- Can my spouse or care partner come with me to visits?
- In most cases yes, and it is often encouraged. Care partners can help with notes, questions, and getting home safely after a long visit. Some study assessments do need to happen one on one, but care partners are usually welcome for the rest of the appointment.
- Will I get a placebo in this trial?
- This is an observational study, so there is no placebo and no experimental treatment is assigned. Researchers observe and collect information while you continue your usual care.
- What procedures are involved in this trial?
- Based on the protocol, this trial involves: Wearable / at-home monitoring (non-invasive). Confirm the full schedule with the study coordinator.