Mediterranean diet slows Parkinson progression
- Trial ID
- NCT06705517
- Official Title
- Mediterranean Diet Effects on Parkinson's Disease (MED-PARK): a Randomized Controlled Trial
- Goal
- Mediterranean diet slows Parkinson progression
- Phase
- NA
- Status
- RECRUITING
- Sponsor
- Università degli Studi dell'Insubria
- Study Type
- INTERVENTIONAL
- Enrollment
- 44 participants
- Conditions
- Parkinson, Parkinson Disease, Parkinson Disease, Idiopathic, PARKINSON DISEASE (Disorder)
- Interventions
- Mediterranean Diet
Plain-Language Summary
Aiming to see whether switching to a Mediterranean diet can ease symptoms or slow progression in Parkinson's by lowering inflammation and shifting the gut microbiome, both of which may affect motor and non-motor problems. Participants randomized to the Mediterranean diet will eat more vegetables, fruits, whole grains, legumes, fish and olive oil and less red and processed meat, and researchers will track clinical measures plus blood and stool markers to link those dietary changes to Parkinson's signs; the diet is tested alongside usual Parkinson's medications, not as a replacement. The trial is looking for people 40 to 85 with idiopathic Parkinson's at Hoehn and Yahr stage 3 or lower, who can eat independently, are willing to follow the diet and give blood and stool samples, and who are either medication-naive or on a stable anti-Parkinson's dose; underweight, obese, certain immune conditions, and recent immune-suppressing treatments are excluded.
Locations
- Centre for Research in Medical Pharmacology, Varese, Varese, Italy
Frequently Asked Questions
- What is this trial testing?
- This trial is studying Mediterranean Diet. Aiming to see whether switching to a Mediterranean diet can ease symptoms or slow progression in Parkinson's by lowering inflammation and shifting the gut microbiome, both of which may affect motor and non-motor problems. Participants randomized to the Mediterranean diet will eat more vegetables, fruits, whole grains, legumes, fish and olive oil and less red and processed meat, and researchers will track clinical measures plus blood and stool markers to link those dietary changes to Parkinson's signs; the diet is tested alongside usual Parkinson's medications, not as a replacement. The trial is looking for people 40 to 85 with idiopathic Parkinson's at Hoehn and Yahr stage 3 or lower, who can eat independently, are willing to follow the diet and give blood and stool samples, and who are either medication-naive or on a stable anti-Parkinson's dose; underweight, obese, certain immune conditions, and recent immune-suppressing treatments are excluded.
- Who can participate?
- Participants must be between 40 Years and 85 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- No. There is no cost to participate. Study-related care and treatment are provided at no charge.
- How long does the trial last?
- This trial is estimated to last approximately 1 year.