Parkinson's Trial NCT06848192
Link gut microbiome to tremor
- Trial ID
- NCT06848192
- Official Title
- The Parkinson's Disease Case-Control Study: Gut Microbiome Study for Parkinson's Disease
- Goal
- Link gut microbiome to tremor
- Status
- RECRUITING
- Sponsor
- Westlake University
- Study Type
- OBSERVATIONAL
- Enrollment
- 40 participants
- Conditions
- Parkinson Disease
Summary For Families
They want to find specific differences in the gut microbiome that are linked to Parkinson's, which could help explain disease mechanisms or point to future biomarkers or therapies. To do that, researchers will collect and compare gut microbiome samples and clinical data from people with Parkinson's and closely matched healthy volunteers, carefully excluding factors that alter gut bacteria such as recent antibiotic use, inflammatory gut disease, chronic constipation, and certain chronic illnesses. The study is looking for adults 50 to 75 years old with a clinical Parkinson's diagnosis and typical motor signs, plus age- and sex-matched healthy controls with no first-degree relatives with Parkinson's, and everyone must be able to give informed consent.
Locations
- The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China
Frequently Asked Questions
- What is this trial testing?
- This trial is studying an experimental treatment. They want to find specific differences in the gut microbiome that are linked to Parkinson's, which could help explain disease mechanisms or point to future biomarkers or therapies. To do that, researchers will collect and compare gut microbiome samples and clinical data from people with Parkinson's and closely matched healthy volunteers, carefully excluding factors that alter gut bacteria such as recent antibiotic use, inflammatory gut disease, chronic constipation, and certain chronic illnesses. The study is looking for adults 50 to 75 years old with a clinical Parkinson's diagnosis and typical motor signs, plus age- and sex-matched healthy controls with no first-degree relatives with Parkinson's, and everyone must be able to give informed consent.
- Who can participate?
- Participants must be between 50 Years and 75 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- You are never charged a fee to join a legitimate clinical trial, and the study treatment and study-specific tests are provided by the trial sponsor at no charge. In the US, routine care you would receive anyway can still be billed to you or your insurance; coverage rules differ by country, and trials in the UK and Canada usually run through public health systems. Travel, parking, and time are real costs, and some trials reimburse them while others do not. Before enrolling, ask the study coordinator to explain in writing what is and is not covered.
- How long does the trial last?
- This trial is estimated to last approximately 9 months.
- Can I leave the trial if I change my mind?
- Yes. You can withdraw from any clinical trial at any time, for any reason, without affecting your standard medical care. Trials are voluntary by law. The team may ask if you are willing to do a brief exit visit so they can collect safety information, but you are not obligated.
- Can my spouse or care partner come with me to visits?
- In most cases yes, and it is often encouraged. Care partners can help with notes, questions, and getting home safely after a long visit. Some study assessments do need to happen one on one, but care partners are usually welcome for the rest of the appointment.
- Will I get a placebo in this trial?
- This is an observational study, so there is no placebo and no experimental treatment is assigned. Researchers observe and collect information while you continue your usual care.
- What procedures are involved in this trial?
- Based on the protocol, this trial involves: MRI scan (non-invasive). Confirm the full schedule with the study coordinator.