Reduce freezing episodes while walking
- Trial ID
- NCT06848205
- Official Title
- Basal Ganglia Contributions to Transitions in Freezing of Gait and Parkinson's Disease
- Goal
- Reduce freezing episodes while walking
- Phase
- NA
- Status
- RECRUITING
- Sponsor
- University of Minnesota
- Study Type
- INTERVENTIONAL
- Enrollment
- 36 participants
- Conditions
- Freezing of Gait, Parkinson Disease
- Interventions
- OFF Parkinson's Medication(s), OFF Deep Brain Stimulation
Plain-Language Summary
Researchers want to pinpoint what changes in basal ganglia activity trigger freezing of gait, so future treatments could detect or prevent those sudden stops. To do that, people who already have a Medtronic Percept DBS device will briefly stop levodopa and other Parkinson's medications and have their stimulator turned off while the implant records brain signals during walking, letting investigators see the neural patterns that precede or accompany freezing without medication or stimulation masking them. They are looking for adults 21 to 75 with idiopathic Parkinson's who can walk 50 meters without an assistive device and who have had a Percept device activated for at least 3 months, while people with other major neurodegenerative, visual, vestibular, musculoskeletal problems, dementia, or pregnancy are excluded.
Locations
- University of Minnesota, Movement Disorders Lab, Minneapolis, Minnesota, United States
Frequently Asked Questions
- What is this trial testing?
- This trial is studying OFF Parkinson's Medication(s). Researchers want to pinpoint what changes in basal ganglia activity trigger freezing of gait, so future treatments could detect or prevent those sudden stops. To do that, people who already have a Medtronic Percept DBS device will briefly stop levodopa and other Parkinson's medications and have their stimulator turned off while the implant records brain signals during walking, letting investigators see the neural patterns that precede or accompany freezing without medication or stimulation masking them. They are looking for adults 21 to 75 with idiopathic Parkinson's who can walk 50 meters without an assistive device and who have had a Percept device activated for at least 3 months, while people with other major neurodegenerative, visual, vestibular, musculoskeletal problems, dementia, or pregnancy are excluded.
- Who can participate?
- Participants must be between 21 Years and 75 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- No. There is no cost to participate. Study-related care and treatment are provided at no charge.
- How long does the trial last?
- This trial is estimated to last approximately 2 years and 9 months.