Reduce early Parkinsons motor symptoms
- Trial ID
- NCT06874803
- Official Title
- Effect of "Qi-Tonifying, Yang-Warming, and Water-Resolving" Acupuncture and Moxibustion for Motor Symptom Improvement in Early Parkinson's Disease (WARMED): A Randomized Controlled Trial
- Goal
- Reduce early Parkinsons motor symptoms
- Phase
- NA
- Status
- RECRUITING
- Sponsor
- Jiani Wu
- Study Type
- INTERVENTIONAL
- Enrollment
- 60 participants
- Conditions
- Parkinson's Disease (PD)
- Interventions
- Acupuncture and Moxibustion (AM), Sham Acupuncture and Moxibustion (Sham-AM)
Summary For Families
It tests whether a traditional acupuncture plus moxibustion protocol that aims to "tonify qi, warm yang, and resolve water" can improve motor symptoms in people with early, mild-to-moderate Parkinson's. The treatment uses needles at specific points together with localized heat from burning mugwort to stimulate nerves and tissues, and investigators think that sensory stimulation may alter brain and spinal cord signaling, muscle control, or local inflammation; they compare real treatment to a sham procedure to see if effects are specific. Because it is non-drug, it would be used alongside usual Parkinson medications like levodopa rather than replacing them. Enrollment is for people aged 30 to 80 with PD by the 2016 Chinese criteria and Hoehn-Yahr stage under 3, excluding Parkinson-plus syndromes, prior DBS, severe medical or psychiatric conditions, bleeding disorders, recent acupuncture, pregnancy, or recent trial participation.
Locations
- Guang'anmen Hospita, China Academy of Chinese Medical Sciences, Beijing, Beijing Municipality, China
Frequently Asked Questions
- What is this trial testing?
- This trial is studying Acupuncture and Moxibustion (AM). It tests whether a traditional acupuncture plus moxibustion protocol that aims to "tonify qi, warm yang, and resolve water" can improve motor symptoms in people with early, mild-to-moderate Parkinson's. The treatment uses needles at specific points together with localized heat from burning mugwort to stimulate nerves and tissues, and investigators think that sensory stimulation may alter brain and spinal cord signaling, muscle control, or local inflammation; they compare real treatment to a sham procedure to see if effects are specific. Because it is non-drug, it would be used alongside usual Parkinson medications like levodopa rather than replacing them. Enrollment is for people aged 30 to 80 with PD by the 2016 Chinese criteria and Hoehn-Yahr stage under 3, excluding Parkinson-plus syndromes, prior DBS, severe medical or psychiatric conditions, bleeding disorders, recent acupuncture, pregnancy, or recent trial participation.
- Who can participate?
- Participants must be between 30 Years and 80 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- No. There is no cost to participate. Study-related care and treatment are provided at no charge.
- How long does the trial last?
- This trial is estimated to last approximately 1 year and 1 month.
- Will I get the real drug or a placebo?
- It depends on the trial design. Some Parkinson's trials are placebo controlled, meaning a portion of participants get an inactive comparison while others get the experimental treatment. Some use crossover designs so everyone eventually receives the active treatment at some point. Observational trials do not use a placebo at all because they are not testing a new treatment. The consent form for any specific trial spells out the design and your odds of being assigned to placebo before you enroll.
- How often will I need to visit the study site?
- Visit frequency varies by trial. Many Parkinson's studies require an in person visit every 4 to 12 weeks during the active treatment phase, with shorter or longer gaps depending on the design. The site coordinator can give you the full visit schedule before you sign anything, so you know what the time commitment looks like.
- Can I leave the trial if I change my mind?
- Yes. You can withdraw from any clinical trial at any time, for any reason, without affecting your standard medical care. Trials are voluntary by law. The team may ask if you are willing to do a brief exit visit so they can collect safety information, but you are not obligated.
- Will travel or parking be reimbursed?
- Many trials reimburse for parking, mileage, and sometimes lodging if the site is far from your home. Reimbursement policies vary by sponsor and site. When you contact the trial team, ask specifically what is covered and how reimbursement is processed.
- Can my spouse or care partner come with me to visits?
- In most cases yes, and it is often encouraged. Care partners can help with notes, questions, and getting home safely after a long visit. Some study assessments do need to happen one on one, but care partners are usually welcome for the rest of the appointment.