Behavioral task of social percepti… for Parkinson's (NCT06884722)
Improve recognizing emotions and movement
- Trial ID
- NCT06884722
- Official Title
- Social Perception and Dopaminergic Modulation in Patients With Parkinson's Disease: a Functional MRI Study (Park Social-E-Motion)
- Goal
- Improve recognizing emotions and movement
- Phase
- NA
- Status
- RECRUITING
- Sponsor
- Hospices Civils de Lyon
- Study Type
- INTERVENTIONAL
- Enrollment
- 83 participants
- Conditions
- Social Perception in Parkinson's Disease
- Interventions
- Behavioral task of social perception (stage 1), Functional magnetic resonance imaging: 3 Tesla magnetic resonance imaging (stage 2), Neurological and neuropsychological assessments, Neurological assessments of Parkinson's disease symptoms and caregiver burden
Summary For Families
It aims to understand how Parkinson's affects social perception, like recognizing emotions on faces and the meaning of body movements, because these problems can hurt relationships and quality of life even early on. Participants will watch short scenes made of moving dots that show social interactions while researchers record brain activity with a 3 Tesla magnetic resonance imaging scanner, and the study will examine how dopamine-related treatment changes the brain networks for seeing movement and for thinking about others. The work has two parts: a first step to check the task, and an imaging step to measure brain responses. They are looking for adults 30 to 75 years old, people with Parkinson's for at least three years who are on routine dopamine-related medicines and who do not have major cognitive problems, and some healthy volunteers for the imaging part.
Locations
- Service de neurologie - troubles du mouvement et pathologies neuromusculaires, Hôpital neurologique Pierre Wertheimer/GHE, Bron, France
Frequently Asked Questions
- What is this trial testing?
- This trial is studying Behavioral task of social perception (stage 1). It aims to understand how Parkinson's affects social perception, like recognizing emotions on faces and the meaning of body movements, because these problems can hurt relationships and quality of life even early on. Participants will watch short scenes made of moving dots that show social interactions while researchers record brain activity with a 3 Tesla magnetic resonance imaging scanner, and the study will examine how dopamine-related treatment changes the brain networks for seeing movement and for thinking about others. The work has two parts: a first step to check the task, and an imaging step to measure brain responses. They are looking for adults 30 to 75 years old, people with Parkinson's for at least three years who are on routine dopamine-related medicines and who do not have major cognitive problems, and some healthy volunteers for the imaging part.
- Who can participate?
- Participants must be between 30 Years and 75 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- You are never charged a fee to join a legitimate clinical trial, and the study treatment and study-specific tests are provided by the trial sponsor at no charge. In the US, routine care you would receive anyway can still be billed to you or your insurance; coverage rules differ by country, and trials in the UK and Canada usually run through public health systems. Travel, parking, and time are real costs, and some trials reimburse them while others do not. Before enrolling, ask the study coordinator to explain in writing what is and is not covered.
- How long does the trial last?
- This trial is estimated to last approximately 1 year and 9 months.
- Can I leave the trial if I change my mind?
- Yes. You can withdraw from any clinical trial at any time, for any reason, without affecting your standard medical care. Trials are voluntary by law. The team may ask if you are willing to do a brief exit visit so they can collect safety information, but you are not obligated.
- Can my spouse or care partner come with me to visits?
- In most cases yes, and it is often encouraged. Care partners can help with notes, questions, and getting home safely after a long visit. Some study assessments do need to happen one on one, but care partners are usually welcome for the rest of the appointment.
- What procedures are involved in this trial?
- Based on the protocol, this trial involves: MRI scan (non-invasive); Thinking & memory tests (non-invasive). Confirm the full schedule with the study coordinator.