Strength-Endurance Training for Parkinson's (NCT06893055)
Improve walking balance and strength
- Trial ID
- NCT06893055
- Official Title
- Strength-Endurance Circuit Training in Parkinson's Disease: Effects on Disease Severity, Physical Performance, Blood Biomarkers and Quality of Life.
- Goal
- Improve walking balance and strength
- Phase
- NA
- Status
- RECRUITING
- Sponsor
- General University Hospital, Prague
- Study Type
- INTERVENTIONAL
- Enrollment
- 90 participants
- Conditions
- Parkinson Disease, Idiopathic
- Interventions
- Strength-Endurance Training, Endurance Training
Summary For Families
The goal is to find out if adding strength work to regular aerobic exercise gives more benefit for physical abilities, Parkinson's symptoms, blood markers, and quality of life than aerobic exercise alone. Participants will do one-hour training sessions twice a week for 12 weeks, either a combined strength-endurance circuit or endurance-only sessions, with measurements before and after the program and again three months later, and some people will wear a smartwatch to track step counts. The study is looking for adults 18 to 75 with a diagnosis of idiopathic Parkinson's who are on stable Parkinson's medication and have a Hoehn-Yahr score of 2.5 or less; people with deep brain stimulation, freezing episodes, severe posture problems such as camptocormia, inability to walk without support, major other health limits, or who cannot attend at least 70 percent of sessions are excluded.
Locations
- Department of Neurology and Centre of Clinical Neuroscience First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Prague, Czechia
Frequently Asked Questions
- What is this trial testing?
- This trial is studying Strength-Endurance Training. The goal is to find out if adding strength work to regular aerobic exercise gives more benefit for physical abilities, Parkinson's symptoms, blood markers, and quality of life than aerobic exercise alone. Participants will do one-hour training sessions twice a week for 12 weeks, either a combined strength-endurance circuit or endurance-only sessions, with measurements before and after the program and again three months later, and some people will wear a smartwatch to track step counts. The study is looking for adults 18 to 75 with a diagnosis of idiopathic Parkinson's who are on stable Parkinson's medication and have a Hoehn-Yahr score of 2.5 or less; people with deep brain stimulation, freezing episodes, severe posture problems such as camptocormia, inability to walk without support, major other health limits, or who cannot attend at least 70 percent of sessions are excluded.
- Who can participate?
- Participants must be between 18 Years and 75 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- You are never charged a fee to join a legitimate clinical trial, and the study treatment and study-specific tests are provided by the trial sponsor at no charge. In the US, routine care you would receive anyway can still be billed to you or your insurance; coverage rules differ by country, and trials in the UK and Canada usually run through public health systems. Travel, parking, and time are real costs, and some trials reimburse them while others do not. Before enrolling, ask the study coordinator to explain in writing what is and is not covered.
- How long does the trial last?
- This trial is estimated to last approximately 1 year and 9 months.
- Can I leave the trial if I change my mind?
- Yes. You can withdraw from any clinical trial at any time, for any reason, without affecting your standard medical care. Trials are voluntary by law. The team may ask if you are willing to do a brief exit visit so they can collect safety information, but you are not obligated.
- Can my spouse or care partner come with me to visits?
- In most cases yes, and it is often encouraged. Care partners can help with notes, questions, and getting home safely after a long visit. Some study assessments do need to happen one on one, but care partners are usually welcome for the rest of the appointment.
- Will I get a placebo in this trial?
- This trial has a group that receives no study treatment (you would continue your usual care) alongside the treatment groups. Because assignment is random, you have about a 1 in 3 chance (roughly 33%) of being in the no-treatment group, assuming the groups are filled equally. Ask the coordinator to confirm the exact assignment ratio.
- How many visits does this trial involve?
- You will come to the clinic twice a week for 1-hour training sessions during a 12-week intervention, with outcome measurements before and after the 12-week intervention and a 3-month follow-up.