Deep Brain Stimulation for Parkinson's (NCT06911229)
Reduce freezing episodes during walking
- Trial ID
- NCT06911229
- Official Title
- Neurophysiology of Locomotor Adaptation and Freezing of Gait in Parkinson's Disease
- Goal
- Reduce freezing episodes during walking
- Phase
- NA
- Status
- RECRUITING
- Sponsor
- University of Florida
- Study Type
- INTERVENTIONAL
- Enrollment
- 60 participants
- Conditions
- Parkinson Disease
- Interventions
- Deep Brain Stimulation (DBS)
Summary For Families
The goal is to pinpoint how the brain circuits that control walking break down in Parkinson's, especially during freezing of gait and when people have to adapt their steps. The team will study people who already have chronically implanted, optimized deep brain stimulation, recording brain signals while participants walk so researchers can see how the electrical stimulation, which sends continuous pulses to motor circuits to normalize abnormal signals and improve movement, relates to freezing and gait adaptation. They are enrolling adults 18 to 80 with a confirmed idiopathic Parkinson's diagnosis who have had stable DBS for at least six months, are ambulatory without walking aids, and do not have dementia or other neurologic conditions like atypical parkinsonism.
Locations
- University of Florida, Gainesville, Florida, United States
Frequently Asked Questions
- What is this trial testing?
- This trial is studying Deep Brain Stimulation (DBS). The goal is to pinpoint how the brain circuits that control walking break down in Parkinson's, especially during freezing of gait and when people have to adapt their steps. The team will study people who already have chronically implanted, optimized deep brain stimulation, recording brain signals while participants walk so researchers can see how the electrical stimulation, which sends continuous pulses to motor circuits to normalize abnormal signals and improve movement, relates to freezing and gait adaptation. They are enrolling adults 18 to 80 with a confirmed idiopathic Parkinson's diagnosis who have had stable DBS for at least six months, are ambulatory without walking aids, and do not have dementia or other neurologic conditions like atypical parkinsonism.
- Who can participate?
- Participants must be between 18 Years and 80 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- You are never charged a fee to join a legitimate clinical trial, and the study treatment and study-specific tests are provided by the trial sponsor at no charge. In the US, routine care you would receive anyway can still be billed to you or your insurance; coverage rules differ by country, and trials in the UK and Canada usually run through public health systems. Travel, parking, and time are real costs, and some trials reimburse them while others do not. Before enrolling, ask the study coordinator to explain in writing what is and is not covered.
- How long does the trial last?
- This trial is estimated to last approximately 1 year and 10 months.
- Can I leave the trial if I change my mind?
- Yes. You can withdraw from any clinical trial at any time, for any reason, without affecting your standard medical care. Trials are voluntary by law. The team may ask if you are willing to do a brief exit visit so they can collect safety information, but you are not obligated.
- Can my spouse or care partner come with me to visits?
- In most cases yes, and it is often encouraged. Care partners can help with notes, questions, and getting home safely after a long visit. Some study assessments do need to happen one on one, but care partners are usually welcome for the rest of the appointment.
- Will I get a placebo in this trial?
- This is a crossover trial: instead of staying in one group, you move through a sequence of assignments, so you receive the active treatment during at least one period of the study. Ask the coordinator for the exact sequence and how long each phase lasts.
- What procedures are involved in this trial?
- Based on the protocol, this trial involves: Brain surgery / implanted device (invasive). Confirm the full schedule with the study coordinator.