Reduce freezing episodes during walking
- Trial ID
- NCT06911229
- Official Title
- Neurophysiology of Locomotor Adaptation and Freezing of Gait in Parkinson's Disease
- Goal
- Reduce freezing episodes during walking
- Phase
- NA
- Status
- RECRUITING
- Sponsor
- University of Florida
- Study Type
- INTERVENTIONAL
- Enrollment
- 60 participants
- Conditions
- Parkinson Disease
- Interventions
- Deep Brain Stimulation (DBS)
Plain-Language Summary
The goal is to pinpoint how the brain circuits that control walking break down in Parkinson's, especially during freezing of gait and when people have to adapt their steps. The team will study people who already have chronically implanted, optimized deep brain stimulation, recording brain signals while participants walk so researchers can see how the electrical stimulation, which sends continuous pulses to motor circuits to normalize abnormal signals and improve movement, relates to freezing and gait adaptation. They are enrolling adults 18 to 80 with a confirmed idiopathic Parkinson's diagnosis who have had stable DBS for at least six months, are ambulatory without walking aids, and do not have dementia or other neurologic conditions like atypical parkinsonism.
Locations
- University of Florida, Gainesville, Florida, United States
Frequently Asked Questions
- What is this trial testing?
- This trial is studying Deep Brain Stimulation (DBS). The goal is to pinpoint how the brain circuits that control walking break down in Parkinson's, especially during freezing of gait and when people have to adapt their steps. The team will study people who already have chronically implanted, optimized deep brain stimulation, recording brain signals while participants walk so researchers can see how the electrical stimulation, which sends continuous pulses to motor circuits to normalize abnormal signals and improve movement, relates to freezing and gait adaptation. They are enrolling adults 18 to 80 with a confirmed idiopathic Parkinson's diagnosis who have had stable DBS for at least six months, are ambulatory without walking aids, and do not have dementia or other neurologic conditions like atypical parkinsonism.
- Who can participate?
- Participants must be between 18 Years and 80 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- No. There is no cost to participate. Study-related care and treatment are provided at no charge.
- How long does the trial last?
- This trial is estimated to last approximately 3 years and 5 months.