Steady infusion reduces off periods

Trial ID
NCT06937034
Official Title
Observational Retrospective CoHort Study on Practical ExperienceS of Treatment With Foslevodopa/foScaRbidopa in Advanced Parkinson's Disease
Goal
Steady infusion reduces off periods
Status
RECRUITING
Sponsor
AbbVie
Study Type
OBSERVATIONAL
Enrollment
2000 participants
Conditions
Parkinson's Disease

Plain-Language Summary

The goal is to collect real-world, practical experience with continuous subcutaneous foslevodopa/foscarbidopa for people with advanced Parkinson's who have troublesome motor fluctuations and off periods on oral levodopa. The work is a retrospective look at patients treated in routine care, and the medication consists of prodrugs that are converted into levodopa and carbidopa after infusion, delivering steady levodopa levels through a small pump to smooth on/off swings and often reduce the need for frequent oral levodopa doses. Eligible participants are adults 18 and older with levodopa-responsive idiopathic Parkinson's who were prescribed the LDp/CDp continuous subcutaneous infusion and enrolled in the AbbVie Patient Support Program.

Locations

  • Medizinische Universitaet Graz /ID# 278569, Graz, Styria, Austria
  • Medisch Spectrum Twente /ID# 276695, Enschede, Overijssel, Netherlands
  • Universitatea De Medicină Și Farmacie Victor Babeș /ID# 276720, Timișoara, Timiș County, Romania
  • Karolinska University Hospital Solna /ID# 277116, Solna, Stockholm County, Sweden

Frequently Asked Questions

What is this trial testing?
This trial is studying an experimental treatment. The goal is to collect real-world, practical experience with continuous subcutaneous foslevodopa/foscarbidopa for people with advanced Parkinson's who have troublesome motor fluctuations and off periods on oral levodopa. The work is a retrospective look at patients treated in routine care, and the medication consists of prodrugs that are converted into levodopa and carbidopa after infusion, delivering steady levodopa levels through a small pump to smooth on/off swings and often reduce the need for frequent oral levodopa doses. Eligible participants are adults 18 and older with levodopa-responsive idiopathic Parkinson's who were prescribed the LDp/CDp continuous subcutaneous infusion and enrolled in the AbbVie Patient Support Program.
Who can participate?
Participants must be at least 18 Years.
Where is this trial located?
This trial is recruiting at 4 locations.
Does it cost anything to join?
No. There is no cost to participate. Study-related care and treatment are provided at no charge.
How long does the trial last?
This trial is estimated to last approximately 8 months.

View on ClinicalTrials.gov