MPPG for Parkinson's (NCT06957405)
Reduce freezing during walking remotely
- Trial ID
- NCT06957405
- Official Title
- Effects of a Remote Mental and Physical Practice Intervention on Freezing of Gait in People With Parkinson's Disease: a Randomized Controlled Trial
- Goal
- Reduce freezing during walking remotely
- Phase
- NA
- Status
- RECRUITING
- Sponsor
- University of Sao Paulo General Hospital
- Study Type
- INTERVENTIONAL
- Enrollment
- 50 participants
- Conditions
- Parkinson Disease, Freezing of Gait
- Interventions
- MPPG (Mental and Physical Practice Group), PPG (Physical Practice Group)
Summary For Families
The trial is testing whether adding guided mental practice using Dynamic Neuro-Cognitive Imagery to regular physical practice can reduce freezing of gait and improve movement and thinking in people with Parkinson's. Sessions are done at home over secure video calls with trained physiotherapists, with 10 supervised sessions of 45 to 60 minutes across six weeks; the experimental group does first-person kinesthetic mental practice paired with matching physical practice, while the control group does the same physical practice but replaces the mental practice with seated stretching. Effects are measured with a timed turn test and the percent of time spent freezing, plus questionnaires and cognitive checks at the start, after the program, and 30 days later, and safety steps like environmental checks and caregiver presence are used during sessions. The study is for people with idiopathic Parkinson's who are taking Parkinson's medication that boosts dopamine, currently experience freezing of gait, can walk independently at home, and have internet and a video device; people with other neurological disorders, major heart or lung problems, uncorrected vision or hearing loss, a score below 12 on the Telephone Montreal Cognitive Assessment, or a score below 20 on the Kinesthetic and Visual Imagery Questionnaire are excluded.
Locations
- University of Sao Paulo, São Paulo, São Paulo, Brazil
Frequently Asked Questions
- What is this trial testing?
- This trial is studying MPPG (Mental and Physical Practice Group). The trial is testing whether adding guided mental practice using Dynamic Neuro-Cognitive Imagery to regular physical practice can reduce freezing of gait and improve movement and thinking in people with Parkinson's. Sessions are done at home over secure video calls with trained physiotherapists, with 10 supervised sessions of 45 to 60 minutes across six weeks; the experimental group does first-person kinesthetic mental practice paired with matching physical practice, while the control group does the same physical practice but replaces the mental practice with seated stretching. Effects are measured with a timed turn test and the percent of time spent freezing, plus questionnaires and cognitive checks at the start, after the program, and 30 days later, and safety steps like environmental checks and caregiver presence are used during sessions. The study is for people with idiopathic Parkinson's who are taking Parkinson's medication that boosts dopamine, currently experience freezing of gait, can walk independently at home, and have internet and a video device; people with other neurological disorders, major heart or lung problems, uncorrected vision or hearing loss, a score below 12 on the Telephone Montreal Cognitive Assessment, or a score below 20 on the Kinesthetic and Visual Imagery Questionnaire are excluded.
- Who can participate?
- Eligibility criteria vary. Check the full listing on ClinicalTrials.gov for detailed inclusion and exclusion criteria.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- You are never charged a fee to join a legitimate clinical trial, and the study treatment and study-specific tests are provided by the trial sponsor at no charge. In the US, routine care you would receive anyway can still be billed to you or your insurance; coverage rules differ by country, and trials in the UK and Canada usually run through public health systems. Travel, parking, and time are real costs, and some trials reimburse them while others do not. Before enrolling, ask the study coordinator to explain in writing what is and is not covered.
- How long does the trial last?
- This trial is estimated to last approximately 6 months.
- Can I leave the trial if I change my mind?
- Yes. You can withdraw from any clinical trial at any time, for any reason, without affecting your standard medical care. Trials are voluntary by law. The team may ask if you are willing to do a brief exit visit so they can collect safety information, but you are not obligated.
- Can my spouse or care partner come with me to visits?
- In most cases yes, and it is often encouraged. Care partners can help with notes, questions, and getting home safely after a long visit. Some study assessments do need to happen one on one, but care partners are usually welcome for the rest of the appointment.
- Will I get a placebo in this trial?
- There is no placebo group. Everyone receives an active treatment; the study compares one treatment against another.
- How many visits does this trial involve?
- You will have 10 remote video-supervised training sessions, each lasting 45-60 minutes, across six weeks, with assessments at baseline, post-intervention, and a 30-day follow-up.
- What procedures are involved in this trial?
- Based on the protocol, this trial involves: Questionnaires & surveys (non-invasive); Thinking & memory tests (non-invasive). Confirm the full schedule with the study coordinator.