Reduce freezing episodes during walking
- Trial ID
- NCT06982638
- Official Title
- Accelerated TMS for Freezing of Gait in Parkinson's Disease
- Goal
- Reduce freezing episodes during walking
- Phase
- NA
- Status
- RECRUITING
- Sponsor
- Medical University of South Carolina
- Study Type
- INTERVENTIONAL
- Enrollment
- 12 participants
- Conditions
- Parkinson's Disease (PD)
- Interventions
- TMS+ Gait training
Plain-Language Summary
They want to reduce freezing of gait, those sudden stops in walking that make movement unsafe and limit independence. The approach pairs accelerated transcranial magnetic stimulation, which uses targeted magnetic pulses to boost activity in brain regions that control walking, with guided gait training to help retrain those circuits; TMS is noninvasive and is intended to add to, not replace, existing Parkinson medications, so dosing should be stable. Looking for people 50 to 80 years old with Parkinson's who have confirmed freezing on a standard questionnaire and on exam, who can complete walk tests without an assist device, and who have had no recent changes to dopaminergic meds. People with seizure history, implanted electronic or metal devices, major non‑PD gait problems, significant cognitive or psychotic disorders, pregnancy, or any MRI/TMS safety concerns are excluded, and enrollment is small.
Locations
- Medical University of South Carlina, Charleston, South Carolina, United States
Frequently Asked Questions
- What is this trial testing?
- This trial is studying TMS+ Gait training. They want to reduce freezing of gait, those sudden stops in walking that make movement unsafe and limit independence. The approach pairs accelerated transcranial magnetic stimulation, which uses targeted magnetic pulses to boost activity in brain regions that control walking, with guided gait training to help retrain those circuits; TMS is noninvasive and is intended to add to, not replace, existing Parkinson medications, so dosing should be stable. Looking for people 50 to 80 years old with Parkinson's who have confirmed freezing on a standard questionnaire and on exam, who can complete walk tests without an assist device, and who have had no recent changes to dopaminergic meds. People with seizure history, implanted electronic or metal devices, major non‑PD gait problems, significant cognitive or psychotic disorders, pregnancy, or any MRI/TMS safety concerns are excluded, and enrollment is small.
- Who can participate?
- Participants must be between 50 Years and 80 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- No. There is no cost to participate. Study-related care and treatment are provided at no charge.
- How long does the trial last?
- This trial is estimated to last approximately 2 years and 1 month.