Determine side that reduces freezing
- Trial ID
- NCT06994728
- Official Title
- Characterization of Subthalamic Nucleus Deep Brain Stimulation Laterality on Visuospatial Attention and Correlation to Freezing of Gait in Parkinson's Disease
- Goal
- Determine side that reduces freezing
- Phase
- NA
- Status
- RECRUITING
- Sponsor
- Medical University of South Carolina
- Study Type
- INTERVENTIONAL
- Enrollment
- 12 participants
- Conditions
- Parkinson Disease, Gait Disorders, Neurologic, Visuospatial/Perceptual Abilities
- Interventions
- Left STN-DBS on, right STN-DBS off first, Right STN-DBS on, left STN-DBS off first
Plain-Language Summary
The team wants to know whether turning on deep brain stimulation on the left versus the right subthalamic nucleus changes visuospatial attention, and whether those side-specific effects are linked to freezing of gait in Parkinson's. To find out, they will temporarily switch bilateral STN-DBS so only one side is on at a time and test attention and gait; STN-DBS delivers targeted electrical pulses to the subthalamic nucleus to modulate motor and related cognitive circuits, which helps movement but can sometimes alter attention depending on the side stimulated. Adults 18 and older who already have bilateral STN-DBS and experience freezing of gait can join, while people with dementia, uncorrected vision or hearing problems, or who are pregnant are excluded.
Locations
- Medical University of South Carolina, Charleston, South Carolina, United States
Frequently Asked Questions
- What is this trial testing?
- This trial is studying Left STN-DBS on, right STN-DBS off first. The team wants to know whether turning on deep brain stimulation on the left versus the right subthalamic nucleus changes visuospatial attention, and whether those side-specific effects are linked to freezing of gait in Parkinson's. To find out, they will temporarily switch bilateral STN-DBS so only one side is on at a time and test attention and gait; STN-DBS delivers targeted electrical pulses to the subthalamic nucleus to modulate motor and related cognitive circuits, which helps movement but can sometimes alter attention depending on the side stimulated. Adults 18 and older who already have bilateral STN-DBS and experience freezing of gait can join, while people with dementia, uncorrected vision or hearing problems, or who are pregnant are excluded.
- Who can participate?
- Participants must be at least 18 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- No. There is no cost to participate. Study-related care and treatment are provided at no charge.
- How long does the trial last?
- This trial is estimated to last approximately 1 year and 2 months.