Predict Parkinson progression using neuroimaging
- Trial ID
- NCT07024875
- Official Title
- Precision Neuroimaging of Parkinson's Disease
- Goal
- Predict Parkinson progression using neuroimaging
- Status
- RECRUITING
- Sponsor
- Washington University School of Medicine
- Study Type
- OBSERVATIONAL
- Enrollment
- 120 participants
- Conditions
- Parkinsons Disease (PD)
Plain-Language Summary
The goal is to use high-precision MRI to identify brain markers that track Parkinson's progression and link specific brain changes to motor and cognitive symptoms, so diagnosis and care can be more personalized. The approach is non-invasive advanced neuroimaging, using structural and functional MRI to map brain anatomy and activity patterns; the scans do not change your medications or interact with levodopa, they just let researchers see how brain circuits relate to symptoms. They are enrolling adults 50 and older with a clinical diagnosis of Parkinson's who do not meet criteria for dementia, plus healthy volunteers with normal cognition and no first-degree relatives with PD, and they exclude people with other neurological or serious medical or psychiatric conditions, major head injury, or MRI contraindications like metal implants or claustrophobia.
Locations
- East Imaging Building, St Louis, Missouri, United States
Frequently Asked Questions
- What is this trial testing?
- This trial is studying an experimental treatment. The goal is to use high-precision MRI to identify brain markers that track Parkinson's progression and link specific brain changes to motor and cognitive symptoms, so diagnosis and care can be more personalized. The approach is non-invasive advanced neuroimaging, using structural and functional MRI to map brain anatomy and activity patterns; the scans do not change your medications or interact with levodopa, they just let researchers see how brain circuits relate to symptoms. They are enrolling adults 50 and older with a clinical diagnosis of Parkinson's who do not meet criteria for dementia, plus healthy volunteers with normal cognition and no first-degree relatives with PD, and they exclude people with other neurological or serious medical or psychiatric conditions, major head injury, or MRI contraindications like metal implants or claustrophobia.
- Who can participate?
- Participants must be at least 40 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- No. There is no cost to participate. Study-related care and treatment are provided at no charge.
- How long does the trial last?
- This trial is estimated to last approximately 5 years and 5 months.