Vitamin D for Parkinson's (NCT07084597)
Stabilize heart and blood pressure
- Trial ID
- NCT07084597
- Official Title
- Effect of Vitamin D3 Supplementation on Cardiac Autonomic Nerve Function in Male
- Goal
- Stabilize heart and blood pressure
- Phase
- NA
- Status
- RECRUITING
- Sponsor
- Bangladesh Medical University
- Study Type
- INTERVENTIONAL
- Enrollment
- 15 participants
- Conditions
- Parkinson Disease
- Interventions
- Vitamin D
Summary For Families
It's testing whether correcting vitamin D3 deficiency can improve cardiac autonomic nerve function, which in Parkinson's can show up as abnormal heart rate variability and blood pressure changes. Participants will take vitamin D3 to raise blood levels, because vitamin D helps regulate calcium balance and has anti-inflammatory and neuroprotective effects that may stabilize autonomic signaling to the heart, and the supplement is given alongside levodopa while calcium levels are monitored. Men aged 51 to 70 with mild to moderate Parkinson's (Hoehn and Yahr I,III), BMI 18.5,24.9, who are vitamin D deficient or insufficient and are taking levodopa are eligible. People with major organ disease, hypercalcemia, current use of antioxidant vitamins or certain heart, blood pressure or sedative drugs, or those already doing yoga or breathing exercises are excluded.
Locations
- Bangladesh Medical University, Dhaka, Shahbag, Bangladesh
Frequently Asked Questions
- What is this trial testing?
- This trial is studying Vitamin D. It's testing whether correcting vitamin D3 deficiency can improve cardiac autonomic nerve function, which in Parkinson's can show up as abnormal heart rate variability and blood pressure changes. Participants will take vitamin D3 to raise blood levels, because vitamin D helps regulate calcium balance and has anti-inflammatory and neuroprotective effects that may stabilize autonomic signaling to the heart, and the supplement is given alongside levodopa while calcium levels are monitored. Men aged 51 to 70 with mild to moderate Parkinson's (Hoehn and Yahr I,III), BMI 18.5,24.9, who are vitamin D deficient or insufficient and are taking levodopa are eligible. People with major organ disease, hypercalcemia, current use of antioxidant vitamins or certain heart, blood pressure or sedative drugs, or those already doing yoga or breathing exercises are excluded.
- Who can participate?
- Participants must be between 51 Years and 70 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- You are never charged a fee to join a legitimate clinical trial, and the study treatment and study-specific tests are provided by the trial sponsor at no charge. In the US, routine care you would receive anyway can still be billed to you or your insurance; coverage rules differ by country, and trials in the UK and Canada usually run through public health systems. Travel, parking, and time are real costs, and some trials reimburse them while others do not. Before enrolling, ask the study coordinator to explain in writing what is and is not covered.
- How long does the trial last?
- This trial is estimated to last approximately 3 months.
- Can I leave the trial if I change my mind?
- Yes. You can withdraw from any clinical trial at any time, for any reason, without affecting your standard medical care. Trials are voluntary by law. The team may ask if you are willing to do a brief exit visit so they can collect safety information, but you are not obligated.
- Can my spouse or care partner come with me to visits?
- In most cases yes, and it is often encouraged. Care partners can help with notes, questions, and getting home safely after a long visit. Some study assessments do need to happen one on one, but care partners are usually welcome for the rest of the appointment.
- Will I get a placebo in this trial?
- Everyone in this trial receives the experimental treatment. There is no placebo group.