Stabilize heart and blood pressure
- Trial ID
- NCT07084597
- Official Title
- Effect of Vitamin D3 Supplementation on Cardiac Autonomic Nerve Function in Male
- Goal
- Stabilize heart and blood pressure
- Phase
- NA
- Status
- RECRUITING
- Sponsor
- Bangladesh Medical University
- Study Type
- INTERVENTIONAL
- Enrollment
- 15 participants
- Conditions
- Parkinson Disease
- Interventions
- Vitamin D
Plain-Language Summary
It's testing whether correcting vitamin D3 deficiency can improve cardiac autonomic nerve function, which in Parkinson's can show up as abnormal heart rate variability and blood pressure changes. Participants will take vitamin D3 to raise blood levels, because vitamin D helps regulate calcium balance and has anti-inflammatory and neuroprotective effects that may stabilize autonomic signaling to the heart, and the supplement is given alongside levodopa while calcium levels are monitored. Men aged 51 to 70 with mild to moderate Parkinson's (Hoehn and Yahr I,III), BMI 18.5,24.9, who are vitamin D deficient or insufficient and are taking levodopa are eligible. People with major organ disease, hypercalcemia, current use of antioxidant vitamins or certain heart, blood pressure or sedative drugs, or those already doing yoga or breathing exercises are excluded.
Locations
- Bangladesh Medical University, Dhaka, Shahbag, Bangladesh
Frequently Asked Questions
- What is this trial testing?
- This trial is studying Vitamin D. It's testing whether correcting vitamin D3 deficiency can improve cardiac autonomic nerve function, which in Parkinson's can show up as abnormal heart rate variability and blood pressure changes. Participants will take vitamin D3 to raise blood levels, because vitamin D helps regulate calcium balance and has anti-inflammatory and neuroprotective effects that may stabilize autonomic signaling to the heart, and the supplement is given alongside levodopa while calcium levels are monitored. Men aged 51 to 70 with mild to moderate Parkinson's (Hoehn and Yahr I,III), BMI 18.5,24.9, who are vitamin D deficient or insufficient and are taking levodopa are eligible. People with major organ disease, hypercalcemia, current use of antioxidant vitamins or certain heart, blood pressure or sedative drugs, or those already doing yoga or breathing exercises are excluded.
- Who can participate?
- Participants must be between 51 Years and 70 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- No. There is no cost to participate. Study-related care and treatment are provided at no charge.
- How long does the trial last?
- This trial is estimated to last approximately 3 months.