Improve walking speed and stability
- Trial ID
- NCT07105787
- Official Title
- Steps Against the Burden of Parkinson's Disease - TelAviv/Bologna
- Goal
- Improve walking speed and stability
- Phase
- NA
- Status
- RECRUITING
- Sponsor
- University of Kiel
- Study Type
- INTERVENTIONAL
- Enrollment
- 42 participants
- Conditions
- Parkinson Disease, Falls
- Interventions
- SDTT + VR triggered adaptations, Speed-dependent treadmill training (SDTT)
Summary For Families
The goal is to reduce falls and make everyday walking steadier by improving gait stability and adaptability in people with Parkinson's who already have trouble walking. The approach uses speed-dependent treadmill training, where the treadmill automatically matches and challenges your walking speed to retrain step timing and balance, combined with virtual-reality triggered changes that force quick adjustments so your brain and muscles learn to respond better; it is a rehabilitation program that complements usual Parkinson's medications rather than replacing them. They are looking for adults diagnosed with Parkinson's by MDS criteria, Hoehn and Yahr stages I to III, with at least a mild gait problem on the MDS‑UPDRS, who can walk one floor and do not have major cognitive impairment, severe depression, an implanted DBS device, or other health issues that make unsupervised exercise unsafe.
Locations
- Tel-Aviv Sourasky Medical Center, Tel Aviv, Israel
- IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy
Frequently Asked Questions
- What is this trial testing?
- This trial is studying SDTT + VR triggered adaptations. The goal is to reduce falls and make everyday walking steadier by improving gait stability and adaptability in people with Parkinson's who already have trouble walking. The approach uses speed-dependent treadmill training, where the treadmill automatically matches and challenges your walking speed to retrain step timing and balance, combined with virtual-reality triggered changes that force quick adjustments so your brain and muscles learn to respond better; it is a rehabilitation program that complements usual Parkinson's medications rather than replacing them. They are looking for adults diagnosed with Parkinson's by MDS criteria, Hoehn and Yahr stages I to III, with at least a mild gait problem on the MDS‑UPDRS, who can walk one floor and do not have major cognitive impairment, severe depression, an implanted DBS device, or other health issues that make unsupervised exercise unsafe.
- Who can participate?
- Eligibility criteria vary. Check the full listing on ClinicalTrials.gov for detailed inclusion and exclusion criteria.
- Where is this trial located?
- This trial is recruiting at 2 locations.
- Does it cost anything to join?
- No. There is no cost to participate. Study-related care and treatment are provided at no charge.
- How long does the trial last?
- This trial is estimated to last approximately 1 year.
- Will I get the real drug or a placebo?
- It depends on the trial design. Some Parkinson's trials are placebo controlled, meaning a portion of participants get an inactive comparison while others get the experimental treatment. Some use crossover designs so everyone eventually receives the active treatment at some point. Observational trials do not use a placebo at all because they are not testing a new treatment. The consent form for any specific trial spells out the design and your odds of being assigned to placebo before you enroll.
- How often will I need to visit the study site?
- Visit frequency varies by trial. Many Parkinson's studies require an in person visit every 4 to 12 weeks during the active treatment phase, with shorter or longer gaps depending on the design. The site coordinator can give you the full visit schedule before you sign anything, so you know what the time commitment looks like.
- Can I leave the trial if I change my mind?
- Yes. You can withdraw from any clinical trial at any time, for any reason, without affecting your standard medical care. Trials are voluntary by law. The team may ask if you are willing to do a brief exit visit so they can collect safety information, but you are not obligated.
- Will travel or parking be reimbursed?
- Many trials reimburse for parking, mileage, and sometimes lodging if the site is far from your home. Reimbursement policies vary by sponsor and site. When you contact the trial team, ask specifically what is covered and how reimbursement is processed.
- Can my spouse or care partner come with me to visits?
- In most cases yes, and it is often encouraged. Care partners can help with notes, questions, and getting home safely after a long visit. Some study assessments do need to happen one on one, but care partners are usually welcome for the rest of the appointment.