tDCS for Parkinson's (NCT07153692)
Improve swallowing safety and function
- Trial ID
- NCT07153692
- Official Title
- Clinical Efficacy and Mechanism of tDCS for Dysphagia in Patients With Parkinson's Disease
- Goal
- Improve swallowing safety and function
- Phase
- NA
- Status
- RECRUITING
- Sponsor
- Wang Ping
- Study Type
- INTERVENTIONAL
- Enrollment
- 58 participants
- Conditions
- Parkinson's Disease and Parkinsonism, Dysphagia
- Interventions
- tDCS, Conventional Dysphagia Treatment, sham tDCS
Summary For Families
The goal is to improve swallowing safety and function in people with Parkinson's disease or related disorders, lowering the risk of choking and aspiration. The approach uses transcranial direct current stimulation, a low, noninvasive electrical current applied over the brain areas that control swallowing to boost cortical excitability and plasticity, given alongside standard dysphagia therapy and compared with a sham stimulation. They are looking for adults 18 to 100 with VFSS-confirmed dysphagia and a diagnosis of Parkinson's, MSA, or PSP, who are cognitively intact (MMSE >23), can consent and cooperate, and do not have other causes of dysphagia, active pneumonia, severe organ failure, or metal implants.
Locations
- Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, China
Frequently Asked Questions
- What is this trial testing?
- This trial is studying tDCS. The goal is to improve swallowing safety and function in people with Parkinson's disease or related disorders, lowering the risk of choking and aspiration. The approach uses transcranial direct current stimulation, a low, noninvasive electrical current applied over the brain areas that control swallowing to boost cortical excitability and plasticity, given alongside standard dysphagia therapy and compared with a sham stimulation. They are looking for adults 18 to 100 with VFSS-confirmed dysphagia and a diagnosis of Parkinson's, MSA, or PSP, who are cognitively intact (MMSE >23), can consent and cooperate, and do not have other causes of dysphagia, active pneumonia, severe organ failure, or metal implants.
- Who can participate?
- Participants must be between 18 Years and 100 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- You are never charged a fee to join a legitimate clinical trial, and the study treatment and study-specific tests are provided by the trial sponsor at no charge. In the US, routine care you would receive anyway can still be billed to you or your insurance; coverage rules differ by country, and trials in the UK and Canada usually run through public health systems. Travel, parking, and time are real costs, and some trials reimburse them while others do not. Before enrolling, ask the study coordinator to explain in writing what is and is not covered.
- How long does the trial last?
- This trial is estimated to last approximately 4 years and 5 months.
- Can I leave the trial if I change my mind?
- Yes. You can withdraw from any clinical trial at any time, for any reason, without affecting your standard medical care. Trials are voluntary by law. The team may ask if you are willing to do a brief exit visit so they can collect safety information, but you are not obligated.
- Can my spouse or care partner come with me to visits?
- In most cases yes, and it is often encouraged. Care partners can help with notes, questions, and getting home safely after a long visit. Some study assessments do need to happen one on one, but care partners are usually welcome for the rest of the appointment.
- Will I get a placebo in this trial?
- This trial has 2 groups, and 1 is a sham (a pretend version of the procedure) group. Because assignment is random, you have about a 1 in 2 chance (roughly 50%) of being in the sham group, assuming the groups are filled equally. Ask the coordinator to confirm the exact assignment ratio.
- How many visits does this trial involve?
- You will receive 10 treatment sessions: once daily, 20 minutes per session, 5 times a week for 2 consecutive weeks.
- What procedures are involved in this trial?
- Based on the protocol, this trial involves: MRI scan (non-invasive). Confirm the full schedule with the study coordinator.