Identify neural causes of dysphagia
- Trial ID
- NCT07299448
- Official Title
- Biological Determinants and Neural Compensatory Mechanisms of Oropharyngeal Dysphagia in Parkinson's Disease
- Goal
- Identify neural causes of dysphagia
- Status
- RECRUITING
- Sponsor
- Heinrich-Heine University, Duesseldorf
- Study Type
- OBSERVATIONAL
- Enrollment
- 100 participants
- Conditions
- Parkinsons Disease (PD), Oropharyngeal Dysphagia
Plain-Language Summary
They want to pin down the biological factors and brain compensation patterns that lead to or protect against oropharyngeal dysphagia, the swallowing problems many people with Parkinson's can develop. As an observational study, researchers will use brain MRI, cough reflex and throat-sensation tests, and clinical swallowing assessments to map how sensory loss and altered neural networks relate to swallowing function, they are measuring how the body and brain behave rather than testing a treatment. Adults 18 and older with idiopathic Parkinson's at any disease stage who can eat orally and follow the testing can join, while people with other causes of dysphagia, implanted electronic stimulators or MRI contraindications, or asthma/COPD are excluded.
Locations
- University Hospital Düsseldorf, Düsseldorf, North Rhine-Westphalia, Germany
Frequently Asked Questions
- What is this trial testing?
- This trial is studying an experimental treatment. They want to pin down the biological factors and brain compensation patterns that lead to or protect against oropharyngeal dysphagia, the swallowing problems many people with Parkinson's can develop. As an observational study, researchers will use brain MRI, cough reflex and throat-sensation tests, and clinical swallowing assessments to map how sensory loss and altered neural networks relate to swallowing function, they are measuring how the body and brain behave rather than testing a treatment. Adults 18 and older with idiopathic Parkinson's at any disease stage who can eat orally and follow the testing can join, while people with other causes of dysphagia, implanted electronic stimulators or MRI contraindications, or asthma/COPD are excluded.
- Who can participate?
- Participants must be at least 18 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- No. There is no cost to participate. Study-related care and treatment are provided at no charge.
- How long does the trial last?
- This trial is estimated to last approximately 2 years.