Magnetic pulses reduce movement stiffness
- Trial ID
- NCT07306104
- Official Title
- The Effect of Long-term Treatment of Parkinson's Disease With T-PEMF
- Goal
- Magnetic pulses reduce movement stiffness
- Phase
- NA
- Status
- RECRUITING
- Sponsor
- University of Southern Denmark
- Study Type
- INTERVENTIONAL
- Enrollment
- 90 participants
- Conditions
- PARKINSON DISEASE (Disorder)
- Interventions
- Transcranial pulsed electromagnetic fields (T-PEMF), Sham (No Treatment)
Summary For Families
Testing whether long-term sessions of transcranial pulsed electromagnetic fields can ease motor symptoms and support brain function in people with mild Parkinson's. The treatment uses noninvasive electromagnetic pulses over the scalp to gently modulate brain activity and promote neuroplasticity, and it is compared with a sham procedure while participants stay on their usual, stable Parkinson medications rather than replacing levodopa. Adults 18 and up with idiopathic Parkinson's at Hoehn and Yahr stage 1 or 2 who can follow procedures and have an MMSE score over 22 may qualify; people with brain implants, epilepsy, recent medication changes, certain anticoagulant use, prior stroke, pregnancy, or other neurological disorders are excluded.
Locations
- Odense University Hospital, Odense, Denmark
- University of Southern Denmark, Odense, Denmark
Frequently Asked Questions
- What is this trial testing?
- This trial is studying Transcranial pulsed electromagnetic fields (T-PEMF). Testing whether long-term sessions of transcranial pulsed electromagnetic fields can ease motor symptoms and support brain function in people with mild Parkinson's. The treatment uses noninvasive electromagnetic pulses over the scalp to gently modulate brain activity and promote neuroplasticity, and it is compared with a sham procedure while participants stay on their usual, stable Parkinson medications rather than replacing levodopa. Adults 18 and up with idiopathic Parkinson's at Hoehn and Yahr stage 1 or 2 who can follow procedures and have an MMSE score over 22 may qualify; people with brain implants, epilepsy, recent medication changes, certain anticoagulant use, prior stroke, pregnancy, or other neurological disorders are excluded.
- Who can participate?
- Participants must be at least 18 Years.
- Where is this trial located?
- This trial is recruiting at 2 locations.
- Does it cost anything to join?
- No. There is no cost to participate. Study-related care and treatment are provided at no charge.
- How long does the trial last?
- This trial is estimated to last approximately 1 year and 10 months.
- Will I get the real drug or a placebo?
- It depends on the trial design. Some Parkinson's trials are placebo controlled, meaning a portion of participants get an inactive comparison while others get the experimental treatment. Some use crossover designs so everyone eventually receives the active treatment at some point. Observational trials do not use a placebo at all because they are not testing a new treatment. The consent form for any specific trial spells out the design and your odds of being assigned to placebo before you enroll.
- How often will I need to visit the study site?
- Visit frequency varies by trial. Many Parkinson's studies require an in person visit every 4 to 12 weeks during the active treatment phase, with shorter or longer gaps depending on the design. The site coordinator can give you the full visit schedule before you sign anything, so you know what the time commitment looks like.
- Can I leave the trial if I change my mind?
- Yes. You can withdraw from any clinical trial at any time, for any reason, without affecting your standard medical care. Trials are voluntary by law. The team may ask if you are willing to do a brief exit visit so they can collect safety information, but you are not obligated.
- Will travel or parking be reimbursed?
- Many trials reimburse for parking, mileage, and sometimes lodging if the site is far from your home. Reimbursement policies vary by sponsor and site. When you contact the trial team, ask specifically what is covered and how reimbursement is processed.
- Can my spouse or care partner come with me to visits?
- In most cases yes, and it is often encouraged. Care partners can help with notes, questions, and getting home safely after a long visit. Some study assessments do need to happen one on one, but care partners are usually welcome for the rest of the appointment.