Assess expiratory respiratory muscle strength
- Trial ID
- NCT07308795
- Official Title
- The Ultrasonographic Evaluation of Abdominal Accessory Respiratory Muscle Thickness in Patients With Parkinson's Disease: Correlation With Disease Severity and Expiratory Respiratory Muscle Strength
- Goal
- Assess expiratory respiratory muscle strength
- Status
- RECRUITING
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
- Study Type
- OBSERVATIONAL
- Enrollment
- 36 participants
- Conditions
- Parkinson Disease (PD), Maximum Inspiratory Pressure, Maximum Expiratory Pressure, Abdominal Accessory Respiratory Muscle Thickness
Summary For Families
The goal is to find out whether thinner abdominal accessory breathing muscles, seen on ultrasound, are linked to worse Parkinson's severity and to weaker inhaling and exhaling pressures. The team uses noninvasive ultrasound to measure those muscle thicknesses and standard mouth-pressure tests called maximum inspiratory pressure and maximum expiratory pressure to see if muscle loss matches lower breathing strength, which could help flag respiratory problems earlier and guide breathing-focused care. Adults 18 to 75 with Parkinson's at Hoehn and Yahr stages 1,3, MMSE over 23, and BMI under 30 can join, while active smokers, people with active chest disease or unstable vitals, those whose Parkinson's is not controlled with medication, and Parkinson-plus syndromes are excluded.
Locations
- İstanbul Fizik Tedavi Ve Rehabilitasyon Eğitim Ve Araştirma Hastanesi, Istanbul, BAHÇELİEVLER, Turkey (Türkiye)
Frequently Asked Questions
- What is this trial testing?
- This trial is studying an experimental treatment. The goal is to find out whether thinner abdominal accessory breathing muscles, seen on ultrasound, are linked to worse Parkinson's severity and to weaker inhaling and exhaling pressures. The team uses noninvasive ultrasound to measure those muscle thicknesses and standard mouth-pressure tests called maximum inspiratory pressure and maximum expiratory pressure to see if muscle loss matches lower breathing strength, which could help flag respiratory problems earlier and guide breathing-focused care. Adults 18 to 75 with Parkinson's at Hoehn and Yahr stages 1,3, MMSE over 23, and BMI under 30 can join, while active smokers, people with active chest disease or unstable vitals, those whose Parkinson's is not controlled with medication, and Parkinson-plus syndromes are excluded.
- Who can participate?
- Participants must be between 18 Years and 75 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- No. There is no cost to participate. Study-related care and treatment are provided at no charge.
- How long does the trial last?
- This trial is estimated to last approximately 2 months.
- Will I get the real drug or a placebo?
- It depends on the trial design. Some Parkinson's trials are placebo controlled, meaning a portion of participants get an inactive comparison while others get the experimental treatment. Some use crossover designs so everyone eventually receives the active treatment at some point. Observational trials do not use a placebo at all because they are not testing a new treatment. The consent form for any specific trial spells out the design and your odds of being assigned to placebo before you enroll.
- How often will I need to visit the study site?
- Visit frequency varies by trial. Many Parkinson's studies require an in person visit every 4 to 12 weeks during the active treatment phase, with shorter or longer gaps depending on the design. The site coordinator can give you the full visit schedule before you sign anything, so you know what the time commitment looks like.
- Can I leave the trial if I change my mind?
- Yes. You can withdraw from any clinical trial at any time, for any reason, without affecting your standard medical care. Trials are voluntary by law. The team may ask if you are willing to do a brief exit visit so they can collect safety information, but you are not obligated.
- Will travel or parking be reimbursed?
- Many trials reimburse for parking, mileage, and sometimes lodging if the site is far from your home. Reimbursement policies vary by sponsor and site. When you contact the trial team, ask specifically what is covered and how reimbursement is processed.
- Can my spouse or care partner come with me to visits?
- In most cases yes, and it is often encouraged. Care partners can help with notes, questions, and getting home safely after a long visit. Some study assessments do need to happen one on one, but care partners are usually welcome for the rest of the appointment.