Personalize brain stimulation to symptoms
- Trial ID
- NCT07336199
- Official Title
- Pairing Subjective Patient Rating and Local Field Potentials for DBS Programming
- Goal
- Personalize brain stimulation to symptoms
- Status
- RECRUITING
- Sponsor
- Ludwig-Maximilians - University of Munich
- Study Type
- OBSERVATIONAL
- Enrollment
- 25 participants
- Conditions
- Parkinson's Disease (PD)
- Interventions
- No intervention (observational study)
Plain-Language Summary
The team aims to make deep brain stimulation programming more precise by matching patients' brief symptom and side effect ratings with the brain's electrical signals, so clinicians can pick settings that better control Parkinson's signs. They will record local field potentials, the small electrical rhythms from the subthalamic nucleus captured by sensing-enabled implanted pulse generators, while participants report how they feel, then look for signal patterns that correspond to better or worse symptom control; nothing new is implanted or given, it is observational. About 25 people aged 35 to 80 with clinician-confirmed idiopathic Parkinson's who already have bilateral STN-DBS with a device that can record signals, who can consent and communicate reliably, and who do not have dementia or severe medical or psychiatric conditions are eligible.
Locations
- LMU University Hospital, München, Germany
Frequently Asked Questions
- What is this trial testing?
- This trial is studying No intervention (observational study). The team aims to make deep brain stimulation programming more precise by matching patients' brief symptom and side effect ratings with the brain's electrical signals, so clinicians can pick settings that better control Parkinson's signs. They will record local field potentials, the small electrical rhythms from the subthalamic nucleus captured by sensing-enabled implanted pulse generators, while participants report how they feel, then look for signal patterns that correspond to better or worse symptom control; nothing new is implanted or given, it is observational. About 25 people aged 35 to 80 with clinician-confirmed idiopathic Parkinson's who already have bilateral STN-DBS with a device that can record signals, who can consent and communicate reliably, and who do not have dementia or severe medical or psychiatric conditions are eligible.
- Who can participate?
- Participants must be between 35 Years and 80 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- No. There is no cost to participate. Study-related care and treatment are provided at no charge.
- How long does the trial last?
- This trial is estimated to last approximately 1 year and 7 months.