Improve everyday walking after training
- Trial ID
- NCT07351032
- Official Title
- Neural Mechanism of Skill Transfer in Parkinson's Disease
- Goal
- Improve everyday walking after training
- Phase
- NA
- Status
- RECRUITING
- Sponsor
- McGill University
- Study Type
- INTERVENTIONAL
- Enrollment
- 24 participants
- Conditions
- PARKINSON DISEASE (Disorder)
- Interventions
- Transcranial Magnetic Stimulation Active, Transcranial Magnetic Stimulation Sham
Plain-Language Summary
The goal is to understand and improve how people with Parkinson's transfer newly learned walking skills from practice into everyday steps, because that kind of skill transfer can break down with the disease. The approach pairs split-belt treadmill training with either active or sham transcranial magnetic stimulation, a noninvasive method that uses brief magnetic pulses to temporarily boost or suppress activity in motor brain areas to see if changing brain excitability helps learning stick. Because TMS acts on brain circuits rather than using a drug, the team can directly test neural mechanisms of skill transfer. They are looking for about 24 people aged 50 or older with confirmed idiopathic Parkinson's who can walk 30 minutes unaided, have no freezing of gait or deep brain stimulator, and have normal-ish cognition (MoCA ≥ 25).
Locations
- McGill University - Currie Gymnasium, Montreal, Quebec, Canada
Frequently Asked Questions
- What is this trial testing?
- This trial is studying Transcranial Magnetic Stimulation Active. The goal is to understand and improve how people with Parkinson's transfer newly learned walking skills from practice into everyday steps, because that kind of skill transfer can break down with the disease. The approach pairs split-belt treadmill training with either active or sham transcranial magnetic stimulation, a noninvasive method that uses brief magnetic pulses to temporarily boost or suppress activity in motor brain areas to see if changing brain excitability helps learning stick. Because TMS acts on brain circuits rather than using a drug, the team can directly test neural mechanisms of skill transfer. They are looking for about 24 people aged 50 or older with confirmed idiopathic Parkinson's who can walk 30 minutes unaided, have no freezing of gait or deep brain stimulator, and have normal-ish cognition (MoCA ≥ 25).
- Who can participate?
- Participants must be at least 50 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- No. There is no cost to participate. Study-related care and treatment are provided at no charge.
- How long does the trial last?
- This trial is estimated to last approximately 5 months.