Transcranial Magnetic Stimulation… for Parkinson's (NCT07351032)
Improve everyday walking after training
- Trial ID
- NCT07351032
- Official Title
- Neural Mechanism of Skill Transfer in Parkinson's Disease
- Goal
- Improve everyday walking after training
- Phase
- NA
- Status
- RECRUITING
- Sponsor
- McGill University
- Study Type
- INTERVENTIONAL
- Enrollment
- 24 participants
- Conditions
- PARKINSON DISEASE (Disorder)
- Interventions
- Transcranial Magnetic Stimulation Active, Transcranial Magnetic Stimulation Sham
Summary For Families
The goal is to understand and improve how people with Parkinson's transfer newly learned walking skills from practice into everyday steps, because that kind of skill transfer can break down with the disease. The approach pairs split-belt treadmill training with either active or sham transcranial magnetic stimulation, a noninvasive method that uses brief magnetic pulses to temporarily boost or suppress activity in motor brain areas to see if changing brain excitability helps learning stick. Because TMS acts on brain circuits rather than using a drug, the team can directly test neural mechanisms of skill transfer. They are looking for about 24 people aged 50 or older with confirmed idiopathic Parkinson's who can walk 30 minutes unaided, have no freezing of gait or deep brain stimulator, and have normal-ish cognition (MoCA ≥ 25).
Locations
- McGill University - Currie Gymnasium, Montreal, Quebec, Canada
Frequently Asked Questions
- What is this trial testing?
- This trial is studying Transcranial Magnetic Stimulation Active. The goal is to understand and improve how people with Parkinson's transfer newly learned walking skills from practice into everyday steps, because that kind of skill transfer can break down with the disease. The approach pairs split-belt treadmill training with either active or sham transcranial magnetic stimulation, a noninvasive method that uses brief magnetic pulses to temporarily boost or suppress activity in motor brain areas to see if changing brain excitability helps learning stick. Because TMS acts on brain circuits rather than using a drug, the team can directly test neural mechanisms of skill transfer. They are looking for about 24 people aged 50 or older with confirmed idiopathic Parkinson's who can walk 30 minutes unaided, have no freezing of gait or deep brain stimulator, and have normal-ish cognition (MoCA ≥ 25).
- Who can participate?
- Participants must be at least 50 Years.
- Where is this trial located?
- This trial is recruiting at 1 location.
- Does it cost anything to join?
- You are never charged a fee to join a legitimate clinical trial, and the study treatment and study-specific tests are provided by the trial sponsor at no charge. In the US, routine care you would receive anyway can still be billed to you or your insurance; coverage rules differ by country, and trials in the UK and Canada usually run through public health systems. Travel, parking, and time are real costs, and some trials reimburse them while others do not. Before enrolling, ask the study coordinator to explain in writing what is and is not covered.
- How long does the trial last?
- This trial is estimated to last approximately 5 months.
- Can I leave the trial if I change my mind?
- Yes. You can withdraw from any clinical trial at any time, for any reason, without affecting your standard medical care. Trials are voluntary by law. The team may ask if you are willing to do a brief exit visit so they can collect safety information, but you are not obligated.
- Can my spouse or care partner come with me to visits?
- In most cases yes, and it is often encouraged. Care partners can help with notes, questions, and getting home safely after a long visit. Some study assessments do need to happen one on one, but care partners are usually welcome for the rest of the appointment.
- How many visits does this trial involve?
- You will visit the lab on three occasions; the second and third visits will be at least 48 hours apart.
- What procedures are involved in this trial?
- Based on the protocol, this trial involves: Questionnaires & surveys (non-invasive). Confirm the full schedule with the study coordinator.