Improve walking using resistance training

Trial ID
NCT07378813
Official Title
Comparison of Changes in Neuromuscular and Functional Performance Due to Resistance Training With Low-Load or High-Load in Persons With Parkinson's Disease.
Goal
Improve walking using resistance training
Phase
NA
Status
RECRUITING
Sponsor
University of Miami
Study Type
INTERVENTIONAL
Enrollment
60 participants
Conditions
Activity, Motor
Interventions
Low-Load Resistance Training, High-Load Resistance Training

Plain-Language Summary

The goal is to find whether low-load or high-load resistance training better improves muscle strength, power, and everyday mobility in people with early to mid-stage Parkinson's. Participants will follow supervised weight programs using either lighter weights with higher reps to build muscle endurance and motor control, or heavier weights with lower reps to build strength and power, with the idea that stronger leg and core muscles can improve gait, balance, and transfers. The program is done alongside usual medical care, so it does not replace medications like levodopa and may help medications work better by improving overall movement and functional reserve. They plan to enroll 60 people aged 50 to 85 with Parkinson's at Hoehn and Yahr stages 1 to 3 who can walk 50 meters unassisted and have a MoCA above 18, excluding those with uncontrolled cardiovascular or neuromuscular disease, systemic inflammatory or autoimmune conditions, or unresolved limb injuries that prevent weight training.

Locations

  • Laboratory of Neruomuscular Research and Active Aging, Coral Gables, Florida, United States

Frequently Asked Questions

What is this trial testing?
This trial is studying Low-Load Resistance Training. The goal is to find whether low-load or high-load resistance training better improves muscle strength, power, and everyday mobility in people with early to mid-stage Parkinson's. Participants will follow supervised weight programs using either lighter weights with higher reps to build muscle endurance and motor control, or heavier weights with lower reps to build strength and power, with the idea that stronger leg and core muscles can improve gait, balance, and transfers. The program is done alongside usual medical care, so it does not replace medications like levodopa and may help medications work better by improving overall movement and functional reserve. They plan to enroll 60 people aged 50 to 85 with Parkinson's at Hoehn and Yahr stages 1 to 3 who can walk 50 meters unassisted and have a MoCA above 18, excluding those with uncontrolled cardiovascular or neuromuscular disease, systemic inflammatory or autoimmune conditions, or unresolved limb injuries that prevent weight training.
Who can participate?
Participants must be between 50 Years and 85 Years.
Where is this trial located?
This trial is recruiting at 1 location.
Does it cost anything to join?
No. There is no cost to participate. Study-related care and treatment are provided at no charge.
How long does the trial last?
This trial is estimated to last approximately 1 year and 4 months.

View on ClinicalTrials.gov