Observational for Parkinson's (NCT07381751)

Scores Parkinson movement from video

Trial ID
NCT07381751
Official Title
Artificial Intelligence-assisted MDS-UPDRS Assessment for Parkinson's Disease
Goal
Scores Parkinson movement from video
Status
RECRUITING
Sponsor
Hong Kong University of Science and Technology
Study Type
OBSERVATIONAL
Enrollment
500 participants
Conditions
Parkinson Disease
Interventions
Observational

Summary For Families

The goal is to create and test an artificial intelligence tool that can score the standard Parkinson's motor exam (MDS-UPDRS Part III) from ordinary color video, so scoring is less subjective and easier to use outside specialized clinics. Participants will have the usual clinician-rated motor exam while being filmed with synchronized color and depth video, and those videos will be processed by a deep learning system that estimates the same scores. The AI results will be compared, with reviewers blinded, against the clinicians' ratings using agreement and sensitivity analyses to see how well the tool matches human raters and detects change. The study plans to recruit about 500 adults aged 18 to 95 with clinically established Parkinson's disease from Queen Elizabeth Hospital in Hong Kong who can give consent and be video-recorded, excluding people with major vision, hearing, or musculoskeletal problems or other serious neurologic or systemic conditions that would affect the assessment.

Locations

  • Hong Kong University of Science and Technology, Hong Kong, China
  • Queen Elizabeth Hospital, Hong Kong, Hong Kong

Frequently Asked Questions

What is this trial testing?
This trial is studying Observational. The goal is to create and test an artificial intelligence tool that can score the standard Parkinson's motor exam (MDS-UPDRS Part III) from ordinary color video, so scoring is less subjective and easier to use outside specialized clinics. Participants will have the usual clinician-rated motor exam while being filmed with synchronized color and depth video, and those videos will be processed by a deep learning system that estimates the same scores. The AI results will be compared, with reviewers blinded, against the clinicians' ratings using agreement and sensitivity analyses to see how well the tool matches human raters and detects change. The study plans to recruit about 500 adults aged 18 to 95 with clinically established Parkinson's disease from Queen Elizabeth Hospital in Hong Kong who can give consent and be video-recorded, excluding people with major vision, hearing, or musculoskeletal problems or other serious neurologic or systemic conditions that would affect the assessment.
Who can participate?
Participants must be between 18 Years and 95 Years.
Where is this trial located?
This trial is recruiting at 2 locations.
Does it cost anything to join?
No. There is no cost to participate. Study-related care and treatment are provided at no charge.
How long does the trial last?
This trial is estimated to last approximately 2 years and 9 months.
Can I leave the trial if I change my mind?
Yes. You can withdraw from any clinical trial at any time, for any reason, without affecting your standard medical care. Trials are voluntary by law. The team may ask if you are willing to do a brief exit visit so they can collect safety information, but you are not obligated.
Can my spouse or care partner come with me to visits?
In most cases yes, and it is often encouraged. Care partners can help with notes, questions, and getting home safely after a long visit. Some study assessments do need to happen one on one, but care partners are usually welcome for the rest of the appointment.
Will I get a placebo in this trial?
This is an observational study, so there is no placebo and no experimental treatment is assigned. Researchers observe and collect information while you continue your usual care.

Related Reading

View on ClinicalTrials.gov